How does cortisol secreted?
In bursts
In response to pulsatile secretion of ACTH
Wen is the largest burst of cortisol?
2 hours before waking up
Important overall effects of cortisol
Gluconeogenesis Glycogenolysis Glycogenesis Fat breakdown Fat deposit in the abdomen Opponent to Insulin Increase rate of glomerular filtration
Adrenal cortex deficiency causes
Addison’s Disease