7.9.16

Question 1

N-acetylcysteine: fx

Answer 1

loosen mucus plugs that develop in lungs

Question 2

what is the electron carrier for steroid syn?

Answer 2

NADPH –> only electron carrier used for anabolic processes

Question 3

what is: Job syndrome

Answer 3

failure of helper T lymphocytes to produce IFN-γ

IFN-γ –> potent activator of phagocytic cells ==> neutrophils fail to respond to chemotactic stimuli:

• recurrent staph abscesses
• pruritic eczema
• high IgE
• eosinophil often elevated

Question 4

von Hippel Lindau dz: manifestation

Answer 4

• hemangioblastoma

- RCC

Question 5

Goodpasture synd: Ab to?

Answer 5

type IV collagen

Question 6

what is: Alport synd

Answer 6

defect type IV collagen:

• hereditary glomerular nephritis
• sensorineural hearing loss
• sometimes ocular abnormalities