Abx labs

Question 1

6 Abx that should be avoided in patients if they have a G6DP def?

Answer 1

Cause hemolytic anemia

1. Chloroquine
2. Dapsone
3. Nitrofirantoin
4. Primaquine
5. Probenecid
6. Sulfamethoxazole

Question 2

Patient has a positive coombs test what does it mean and what should be done? 8

Answer 2

• Indicates drug related hemolysis and drug shoul dbe stopped

1. Beta lactam inhibitors
2. Cephalosporins
3. Isoniazid
4. Nitro
5. PCNs
6. Quinine
7. Rifampin
8. Sulfamethoxazole

Question 3

Drug induced lupus 3

Answer 3

1. Isoniazid
2. Minocycline
3. Terbinafine

Question 4

False positive urine glucose 4

Answer 4

• Glucose urine can be elvated due to drug not BG
• PCNs
• Cephs
• Imipenem
• Isoniazid

Question 5

False elevation aPTT 2`

Answer 5

Ortivancin IV UFH contraindicated x 5 days

Televancin IV UFH contraindicated

Question 6

Drugs that cause false elevation of INR? 3

Answer 6

Dapto

Orivancin

Televancin

Question 7

Elevated CPK

Answer 7

Dapto

DC s/sx of myopathy and CPK > 5 x ULN

Or asymptomatic with CPD > 10xULN

Question 8

Abx that are only compatible with saline?

3

Answer 8

Amp

Amp/sul

Etrapenem

Question 9

Two drugs that need light protection during admin?

Answer 9

Doxy micrafungin

Question 10

Isoniazid can cause what 3 lab test?

Answer 10

Positive coombs test indicated hemolysis

DILE

False positive urine glucose

Question 11

Cephalosporins can cause what two lab tests?

Answer 11

Positive coombs test and falso positive urine glucose

Question 12

2 nitro lab tests

Answer 12

G6DP and Positive coombs test