Drug Interactions

Question 1

2C8 Inducers 2

Answer 1

1. Phenytoin
2. Rifampin

Question 2

2C8 Inhibitors 7

Answer 2

1. Amiodarone
2. Atazanavir
3. Clopidogrel
4. gemfibrozil
5. ketoconazole
6. Bactrim
7. ritonavir

Question 3

2C8 Substrates 5

Answer 3

1. Amiodarone
2. Dasabuvir
3. Pioglitazone
4. repaglinide
5. rosiglitazone

Question 4

2C19 substrates 4

Answer 4

1. Clopidogrel
2. Phenytoin
3. Thioridazine
4. voriconazole

Question 5

2C19 Inducers 4

Answer 5

1. Carbamazapine
2. Phenobarbital
3. phenytoin
4. rifampin

Question 6

2C9 Substrates 16

Answer 6

1. Alosetron
2. Carvedilol
3. Celecoxib
4. Diazepam
5. Diclofenac
6. FLuvastatin
7. glyburide
8. gliizide
9. glimepiride
10. meloxecam
11. netaglinide
12. phenytoin
13. Ramelteon
14. S-warfarin
15. tamoxifen
16. zolpidem

Question 7

2C9 Inducers 9

Answer 7

1. Arepitant
2. Carbamazepine
3. Phenobarb
4. Phenytoin
5. Primidone
6. Rifampin
7. Rifepentine
8. ritonavir
9. St Johns

Question 8

2C9 inhibitors 19

Answer 8

1. Amiodarone
2. Atazanavir
3. Capecitebine
4. cimetidine
5. efavirenz
6. etravirine
7. gemfibrozil
8. fluconazole
9. flvoxamine
10. flurouracil
11. isoniazid
12. ketocon
13. metronidazole
14. ortivancin
15. tamoxifen
16. bactrim
17. valpro
18. voriconazole
19. zafurlukast

Question 9

Add 2D6

Question 10

What risk does clopidogrel have with what types of drugs?

Answer 10

Pro drug

risk with 2C19 inhibitors

Dont use with 2C19 inhibtiors including omeprazole and esomeprazole