ID 11

Question 1

What 3 Abx types are concentration dependent killers

Answer 1

1. AGs
2. Quinolones
3. Dapto

Question 2

What 4 abxs are AUC:MIC dep

Answer 2

1. Vanc
2. Macrolides
3. Tetracyclines
4. Polymyxins

Question 3

Only PCN active against Pseudomonas?

Answer 3

Zosyn

Question 4

PCN class effects? 2 Cautions and such

Answer 4

1. Avoid in beta-lactam allergy except pregnant patients with syphilis
2. All PCns increase risk of seizure in renal impairment

Question 5

Cephalosporins are not active againts?

Answer 5

Enterococcus

Question 6

Oral outpatient cephalosporins? 3

Answer 6

1. Gen Cephalexin
   
   1. Common uses skin infections with MSSA and strep through
2. Cefuroxime: Acute otitis media, CAP, sinus infection
3. CAP, sinus infection

Question 7

Common uses for cefazolin?

Answer 7

Surgical prophylaxis

Parenteral

Question 8

10 in patient pareneteral cephs

Answer 8

1. 1st gen: Cefazolin
2. 2nd gen Cefotetan, Cefoxitin
3. 3rd gen: Ceftriaxone and Cefotaxime
4. 3rd gen Ceftazidime, 4th gen Cefepime
5. Ceftolozan/Tazo, Ceftaz/Avibactam
6. Ceftaroline Only beta lactam active against MRSA

Question 9

Class effects of Carbapenems? 4

Answer 9

1. All cover ESBL producing organisms
2. All except ertra cover pseudomonas
3. Dont use with PCN allergy
4. Seizure risk with higher doses, renal failure or use of imipenem/cilstatin

Question 10

All carbapenems dont cover what 5 organisms?

Answer 10

Atypicals, VRE, MRSA, C. DIf, Stenotrophomonas

Question 11

What 3 organisms does ertrapenem not cover?

Answer 11

PSeudomonas, Acinetobacter, or Enterococcus

Question 12

3 common uses of Carbapenems

Answer 12

1. Polymicrobial infections mod severe diabetic foot infections
2. Empiric therapy when resistant organsims are suspected
3. Resttant pseudomonas or Acinetobacter Not ertra

Question 13

What monobactam can be used with PCN allergy?

Answer 13

Aztreonam

Question 14

What are the 3 respiratory quinolones?

Answer 14

Moxi, levo gemi

Question 15

8 abxs that do not require renal dose adjustments?

Answer 15

1. Antistaph PCNS (dicloxacillin, nafcillin)
2. Ceftriaxone
3. Clindamycin
4. Doxy
5. Macrolides (azithro, erythro only)
6. Metronidazole
7. Moxi
8. Linezolid

Question 16

Cardiac or vascular surgery abx proph 2

Answer 16

Cefazolin

Cefuroxime

Question 17

Colorectal suregery abx proph 6 total

Answer 17

1. Cefotetan, cefoxitin, amp/sulbactam, ertra
2. or Metro or ceftriaxone