Actinobacillus (Ex2)

Question 1

Actinobacillus pleuropneumoniae general features

Answer 1

• very important disease in swine rearing

- younger pigs (

Question 2

Actinobacillus pleuropneumoniae virulence factors

Answer 2

• adhesion: fimbriae
• XXX: Fe necessary
• exotoxins: Apx toxins
• capsule
• LPS
• OMPs
• Enzymes
• heat shock proteins

Question 3

Actinobacillus pleuropneumoniae exotoxins

Answer 3

• RTX: make pores in cells
• recombinant toxins: lung lesions’
• 1: strong hemolytic and cytolytic effects
• 2: weak hemolytic and cytolytic effects
• 3: strong cytolytic
• 4: only expressed in vivo, necessary for full virulence

Question 4

Actinobacillus pleuropneumoniae symptoms

Answer 4

• respiratory distress
• general symptoms
• hyperacute: death
• acute: coughing, blood
• fibrinous pleuritis, hemorrhagic nectrotizing pneumonia
• adhesive pleuritis

Question 5

Actinobacillus pleuropneumoniae Diagnosis

Answer 5

• culture: samples need to be fast in lab, not resistant in environment
• slow grower
• NAD dependent
• CO2 enriched media

Question 6

Actinobacillus pleuropneumoniae treatment

Answer 6

• hygiene
• antimicrobials: not much resistance
• vaccine: best with Apx, TBP, and type 4 fimbriae

Question 7

Actinobacillus suis general features

Answer 7

• obligate symbiotic
• facultative pathogenic
• carriers: tonsils and vagina
• pathogenic for mice
• sporadic

Question 8

Actinobacillus suis symptoms

Answer 8

• acute: young animals, mortality
• less acute: older animals, general symptoms, respiratory distress, polyarthritis
• Adult: SQ abscesses, anorexia, fever, meningitis

Question 9

Actinobacillus equuli symptoms

Answer 9

• bronchitis, pleuritis, pneumonia
• foal: septicemia, sleep foal disease, enteritis, slimy pus
• adult: abortions, septicemia, localization in joints

Question 10

Actinobacillus lignieresii general features

Answer 10

• wooden tongue, timber tongue
• obligate symbiont
• facultative pathogen
• inhabitant of nasopharynx

Question 11

Actinobacillus lignieresii etiology

Answer 11

• contaminated surgical material of vet

- lesions at surgical sites

Question 12

Actinobacillus lignieresii lesions

Answer 12

• mainly tongue

- capsule of connective tissue with multiple granulomas containing yellow pus and sulfur granules

Question 13

Ornithobacterium rhinotracheale predisposing factors

Answer 13

• stress
• respiratory infections
• high density
• ventilation
• ammonia concentrations

Question 14

Ornithobacterium rhinotracheale symptoms

Answer 14

• sneezing, nose exudate, coughing, depression, swelling sinus, facial edema, anorexia, dyspnea
• low mortality

Question 15

Ornithobacterium rhinotracheale diagnosis

Answer 15

• bacterial culture: difficult, slow growth, frequently overgrown, needs CO2
• ELISA

Question 16

Ornithobacterium rhinotracheale treatment

Answer 16

• antibiotics

- high resistance