Adaptive Immunity

Question 1

What system is involved?

Answer 1

Lymphatic system

Question 2

Where are WBCs produced and B cells mature

Answer 2

Bone Marrow

Question 3

where do T cells mature

Answer 3

Thymus

Question 4

What filters blood and has B cells?

Answer 4

Spleen

Question 5

What is the traveling route from tissues to lymphnodes?

Answer 5

Lymphatic vessels

Question 6

What is the meeting place for pathogens and WBCs?

Answer 6

Lymphnodes

Question 7

Nonself molecule that generates antibodies

Answer 7

Antigen

Question 8

Region of antigen that is recognized and bound by immune system molecules

Answer 8

Epitope

Question 9

Role of DCs and MOs

Answer 9

Professional APCs

Question 10

Where does APC present antigen to T cell?

Answer 10

Lymph node

Question 11

How is the antigen displayed?

Answer 11

Surface of APC with MHC

Question 12

What is the antigen presented to first?

Answer 12

T cell

Question 13

What does the T cell use to detect/need

Answer 13

CD4 coreceptor, T cell receptor (TCR), cytokines

Question 14

Activated in response to a exogenous pathogen

Answer 14

Humoral response

Question 15

Pathogen outside of host cells

Answer 15

Exogenous

Question 16

In a humoral response, what does the APC present the pathogen on?

Answer 16

MHC 2

Question 17

In a humoral response what is the coreceptor called?

Answer 17

CD 4

Question 18

What cell does the APC present antigen to in a humoral response?

Answer 18

Helper T cell

Question 19

How does the Helper T cell respond to antigen presentation in a humoral response?

Answer 19

Activation and coordination of other WBCS

Question 20

What is an outcome of a helper T cell in the humoral response

Answer 20

Mitosis

Question 21

What cell (not APC) must present antigen to Helper T in a humoral response?

Answer 21

A B cell

Question 22

How does a B cell get a antigen

Answer 22

Comes in contact with pathogen via phagocytosis

Question 23

How does a B cell respond?

Answer 23

Mitosis

Question 24

What cells types can B cells mature into

Answer 24

Plasma cells and memory cells

Question 25

Role of plasma cells

Answer 25

Secrete antibodies

Question 26

Antibodies coat pathogen

Answer 26

Neutralization

Question 27

Antibodies coat pathogen, allowing Macrophage to engulf easier

Answer 27

Opsonization

Question 28

What do antibodies activate?

Answer 28

Eosinophils

Question 29

What can the activation of a helper T cell do to macrophages

Answer 29

Super macrophage

Question 30

Super macrophage abilities

Answer 30

Enhanced attachment to MAMPS, stronger enzymes and toxins in lysosome

Question 31

Activated in response to an endogenous pathogen

Answer 31

Cell mediated response

Question 32

What is the first cell to respond for cell mediated?

Answer 32

Dendritic cell

Question 33

What digests a pathogen in a dendritic cell?

Answer 33

Proteosome

Question 34

What are antigens on for cell mediated?

Answer 34

MHC I

Question 35

What do DCs present antigens to (cell mediated)

Answer 35

Cytotoxic T cells

Question 36

What coreceptor do cytotoxic T cells have?

Answer 36

CD8

Question 37

What happens in a cytotoxic t cell response?

Answer 37

Mitosis

Question 38

What can cytotoxic T cells mature into?

Answer 38

Memory cells or Killer T cells

Question 39

Role of killer T cell

Answer 39

Leaves lymph, surveys tissue for infected cells with antigen

Question 40

What do killer T cells do if they find an infected cell?

Answer 40

Release perforin and granzymes to kill