Basic Population Genetics - Ch.5 - 6 Flashcards

(29 cards)

1
Q

Types of Mutations (8)

A

Point mutation
Insertion
Deletion
Gene Duplication
Inversion
Frameshift mutation
Chromosome Fusion
Genome Duplication

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2
Q

Meiosis

A

Recombination of genetic material

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3
Q

Population Genetics

A

The study of the distribution and frequencies of genotypes and alleles in population

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4
Q

Harvey-Weinberg Equilibrium

A

Theoretical concept of no evolutionary changes.
Able to predict allele frequencies.

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5
Q

Conditions for HWE

A

Population is infinitely large
Genotypes do not confer differences in fitness
No mutation
Mating is random
No migration

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6
Q

Fitness (W)

A

The survival and reproductive success of an individual with a particular phenotype

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7
Q

Components of Fitness

A

Survival to reproductive age
Mating success
Fecundity

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8
Q

Relative Fitness (w)

A

Contribution of individuals with one genotype compared with the average contribution of all individuals in the population

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9
Q

Average Excess Fitness

A

Difference between relative contribution of individuals with one genotype and the average fitness of the populations as a whole

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10
Q

Natural selection is more effective in _____

A

Large populations, because drift is less likely

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11
Q

Genome Sequencing

A

Can pinpoint genetic mechanisms of evolution

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12
Q

Pleiotropy

A

A single gene or mutation influences multiple phenotypic traits

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13
Q

Antagonistic Pleiotropy

A

Beneficial effects for one trait but detrimental effects for other triats

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14
Q

Negative Frequency-Dependent Selection

A

Common phenotypes are selected against and rare phenotypes are favoured

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15
Q

Heterozygote Advantage

A

Heterozygosity confers greater fitness than homozygotes

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16
Q

Mutation-Selection Balance

A

Equilibrium frequency reached through tug-of-war between negative selection on deleterious alleles and new mutations.
Explains persistence of deleterious mutations in populations

17
Q

Inbreeding

A

Brings recessive deleterious allele together

18
Q

Inbreeding Depression

A

the reduction in biological fitness due to inbreeding

19
Q

Inbreeding Coefficient

A

F = the probability that two alleles at any locus of an individual are identical by descent

20
Q

Gene Expression

A

Process by which information from a gene is transformed into a product

21
Q

Order of RNA Processes

A
  1. Transcription
  2. Translation
22
Q

Epigenetic

A

The functional modifications to DNA that don’t involve changes to the sequences of nucleotides.
The study of the heritability of these modifications

23
Q

Epistasis

A

When the effects of an allele at one genetic locus are modified by alleles at one or more other loci

24
Q

Additive

A

Describes an allele that yields twice the phenotypic effect when two copies are present at a given locus. Not influenced by the presence of other alleles.

25
Rare alleles are almost always carried _____
In heterozygous states
26
Landscape Genetics
Field of research that combines population genetics, landscape ecology, and spatial statistics
27
Population Structure
The occurrence of populations that are subdivided by influences that prevent individuals from mixing. Enhances the effects of genetic drift
28
Fst
The measure of genetic distance between subpopulations
29
Gene Flow Counteracts ____
Population subdivision