Ch 3: Stem Cells

Question 1

What are the three main classes of naturally occuring stem cells?

Answer 1

1. embryonic stem cells
2. adult stem cells
3. fetal/perinatal stem cells

Question 2

What are totipotent stem cells?

Answer 2

have the potential to differentiate into cells from each of the germ layer lineages: ectoderm, endoder, mesoderm, as well as extra-embryonic tissue like the trophectoderm

fertilized zygote is an example*

Question 3

What is pluripotent

Answer 3

stem cells that have the capacity to differentiate into cells from more than one germ layer lineage but NOT extra-embryonic tissue
Examples include: embryonic stem cells

Question 4

What are multipotent stem cells?

Answer 4

restricted to the germ layer lineage from which it originates from.
Example: adult stem cells

Question 5

What class is a mesencymal stem cell and what is its potency?

Answer 5

adult stem cell
multipotent
only 1 germ layer differentiation

Question 6

What benefits do mesenchymal stem cells provide?

Answer 6

produce anabolic and anti-inflammatory agents, immunomodulatory/immunosuppressive effects, rapid proliferation
(MSC can be bone, cartilage, fat, muscle)