depressive disorders
a set of disorders characterized by depressed mood and/or anhedonia
dysphoria
an intense feeling of unease, discontent or sadness
Major Depressive Disorder
Disorder involving a sad mood or anhedonia plus 4+ of the symptoms:
weight loss/decrease appetite, insomnia/hypersomnia, fatigue, worthlessness/hopelessness, guilt, trouble concentrating, suicidal ideations for 2+ weeks
Seasonal Affective Disorder (SAD)
Identified by a 2yr period when a person experiences depression during winter months then recovers during summer
peripartum onset
used when depressive/manic episode occurs during pregnancy or in the 4 weeks after childbirth
emotional liability
unstable and quickly shifting moods
Persistent Depressive Disorder
Depression but consecutively for 2 years everyday more days than not
premenstrual dysphoric disorder (PMDD)
characterized by a mixture of depression, anxiety, and tension, irritability. mood swings may occur the week before onset of meses
disruptive mood dysregulation disorder
in children- characterized by immature and inappropriate temper outbursts.
Black Box warning
FDA’s most stringent warning for drugs and medical devices on the market which notify the public and health care providers to serious side effects
Bipolar Disorder
marked by cycles between manic episodes and depressive episodes
Mania
emotional disturbance that involves alteration of manic and depressive episodes
bipolar 1
moods alternate between depressive and manic states
bipolar 2
experiences hypomania
hypomania
milder symptoms of mania but are not severe enough to interfere with daily functioning
cyclothymic disorder
a chronic form of bipolar disorder characterizes by less extreme mood states
rapid cycling bipolar disorder
experiencing 4 or more cycles of mania and depression within 1 year
monoamines
neurotransmitters:
catecholamines (epinephrine, norepinephrine, dopamine) and serotonin that have been implicated in the mood disorders
norepinephrine
regulation of mood
serotonin
regulation of mood and impulsive responses
Hypothalamic-pituitary-adrenal axis (HPA axis)
key components of the neuroendocrine system that work together in a feedback system interconnected with the limbic system and the cerebral cortex
neuroinflammation
an inflammatory response within the brain or spinal cord that occurs in response to disease, injury, infection, or stress
behavioral theories of depression
theories that view depression as resulting form negative life events that represent a reduction in positive reinforcement
Learned Helplessness Theory
suggests that the type of stressful event most likely lead to depression is an uncontrollable negative event