1
Q
Is the pyruvate dehydrogenase complex irreversible
A
- yes
- >it cannot be used to convert acetyl coA to pyruvate or glucose
2
Q
What is the PDH complex difference between that in the nervous system and the liver
A
- in the liver it is activated by insulin
- >in the nervous system, the complex is not responsive to any hormones
3
Q
What inhibits the PDH complex
A
- high levels of acetyl coA due to beta-oxidationn
- > negative feedback
- the buildup of acetyl coA causes a shift in metabolism
- > pyruvate is no longer converted into acetyl-Coa but rather into oxaloacetate
4
Q
What are the three fates of pyruvate
A
1) conversion to acetyl-coA by PDH
2) Conversion to lactatte by lactate dehydrogenase
3) Conversion to oxaloacetate by pyruvate carboxylase
MCAT Biochemistry
flashcards
Decks in class (46)
# Cards
-
Chapter 2.18
-
Chapter 2.27
-
Chapter 2.36
-
Chapter 2.41
-
Chapter 2.57
-
Chapter 3.117
-
Chapter 3.25
-
Chapter 3.319
-
Chapter 4.17
-
Chapter 4.25
-
Chapter 4.33
-
Chapter 4.413
-
Chapter 5.111
-
Chapter 5.217
-
Chapter 5.37
-
Chapter 6.110
-
Chapter 6.28
-
Chapter 6.310
-
Chapter 6.48
-
Chapter 6.514
-
Chapter 7.111
-
Chapter 7.213
-
Chapter 7.310
-
Chapter 7.47
-
Chapter 7.56
-
Chapter 9.15
-
Chapter 9.213
-
Chapter 9.33
-
Chapter 9.44
-
Chapter 9.511
-
Chapter 9.614
-
Chapter 9.74
-
Chapter 12.12
-
Chapter 12.25
-
Chapter 12.32
-
Chapter 12.49
-
Chapter 12.515
-
Chapter 12.610
-
Chapter 10.16
-
Chapter 10.212
-
Chapter 10.310
-
Chapter 8.15
-
Chapter 8.212
-
Chapter 8.32
-
Chapter 8.43
-
Chapter 10.43
