1
Q
How is the Cu absorption in the body ?
A
Slow / partial
2
Q
What is the Cu liberation mecha from the liver ?
A
In case of exhaustion = liberated from mitochondria, nuclei, lysosomes & enz
Reach bloodstream & produce hemolytic crisis
Excretion = bile & plasma prot -> urine
3
Q
Main CS in Cu poisoning :
A
1st phase = Cu accumulation
2nd phase = hemolytic crisis, tremors, icterus, Hburia + skin alterations
4
Q
Which is the colour of the blood in Cu poisoning ?
A
Chocolate Br due to MetHb formation
5
Q
Spe antidote for Cu poisoning ? If yes, which one ?
A
Yes, D-penicillamine & CaNa2-EDTA
+ liver protecting ag & circ support + sympto
Toxico
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