1
Q
Which is the toxic dose for Fe ?
A
3-5x normal dose
Inorga Fe-salts > Fe cplx
2
Q
Which one of Fe2+ & Fe3+ is the most easily absorbed ?
A
Fe2+
3
Q
Transferrin is physiologic at :
A
30-35%
4
Q
Fe is distributed in :
A
Bm, m & organs
Storage = ferritin & hemosiderin
5
Q
Fe elim through :
A
bile = slow
6
Q
Mecha of Fe poisoning :
A
High capillary permeability -> vasc collapse & paralysis + hepatic damage
7
Q
Main Fe poisoning CS =
A
Cyanosis
Paralysis & narcotic-// status
Shock (loss fluids & electrolye)
Dyspnea (pulm edema)
8
Q
Spe antidote for Fe poisoning ? If yes, which one ?
A
Yes, Deferoxamine
9
Q
Anaphylactic cases can occur in Fe poisoning ?
A
Yes -> ttt = norepinephrine, antiHis & Glu
Toxico
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