What is the menstrual cycle?
Changes in uterus (endometrium) in sync with ovarian cycle; prepares for embryo implantation
What does progesterone do in the first stage of the menstrual cycle?
Thickens endometrium, increases blood vessels and glands
What happens after ovulation in the menstrual cycle?
Endometrial glands secrete glycogen-rich mucus
What happens if no fertilisation occurs in the menstrual cycle?
Corpus luteum degenerates, progesterone falls, endometrium breaks down
What is menstruation?
Blood, mucous secretions and cell debris from uterine lining lost through the vagina. Marks day 1 of cycle
What is menarche?
The name given to when menstruation first begins; start of puberty
What is menopause?
Gradual end of cycles, usually ages 45–55; ~35 fertile years; ~400 eggs mature
Summary of the menstrual cycle?
Prepares uterus for pregnancy; without fertilisation, hormone levels fall and menstruation occurs. Starts at menarche and ceases at menopause
What is the ovarian cycle?
A series of events that take place within the ovaries
What does the ovarian cycle include?
Egg maturation, ovulation, follicle/corpus luteum development
How long is the ovarian cycle?
Variable 20–40 days, average 28
How many immature eggs are present at birth?
~400,000 in resting phase, surrounded by primary follicles
What happens at puberty in the ovarian cycle?
FSH and LH increase, promoting follicle development
What is a primary follicle?
Cells enlarge and divide around egg
What is a secondary follicle?
A fluid-filled cavity forms inside the follicle
What is a mature follicle also called?
Graafian follicle; bulges at ovary surface
What is ovulation?
Mature follicle bursts, oocyte released, swept into uterine tube
What does the corpus luteum do?
Secretes oestrogen and progesterone; prepares uterus, inhibits LH and FSH
What happens to the corpus luteum if no fertilisation occurs?
Degenerates to corpus albicans (scar)
What happens to the corpus luteum if fertilisation occurs?
Maintained by HCG until placenta takes over
When do ovarian cycles pause?
During pregnancy and breastfeeding
Summary of the ovarian cycle?
Governs egg maturation, ovulation, and corpus luteum function. Controlled by FSH, LH, and HCG, it synchronises with the menstrual cycle to support reproduction
What happens during days 1-5 of the menstrual cycle?
Menstruation occurs: shedding of the endometrial lining (blood, mucus, cell debris)
What hormone levels are low during menstruation (days 1-5)?
Oestrogen and progesterone