what is depression
at least 2 weeks of anhedonia, low mood and low energy most days
is depression more common in females or males
females
2:1
are men more suicidal or women
men
what is psuedodementia
cognitive and functional impairments that mimic dementia but are secondary to depression
lots of ‘i dont know’ answers
biological risk factors for depression
chronic pain
post partum
steroids
decreased T4
psycholgical risk factors for depression
trauma
low self esteem
abuse
social risk factors for depression
bereavement
divorce
stress
what is the stress vulnerability model
different people have different thresholds before spiraling
what is the monoamine hypothesis
suggests neurotransmitters are indicated in depression
low serotonin, low dopamine, low noradrenaline
symptoms of depression
SIGE CAPS
suicide/self harm
interest low
guilt + worthlessness
energy low
concentration low
appetite low
psychomotor retardation
sleep low
what is atypical depression
high appetite
high sleep
high mood on good occasions
catatonia
very sensitive
treatment for aytpical depression
treatment is CBT+MAOI
what bloods do you do for depression
FBC
U+E
TFT
prolactin
syphillis serology
B12
folate
4 questionnaires for depression
PHQ-9 (most common)
HADS (only in hospital)
BD1-11 (self reporting)
Edinburgh (post natal)
how to score PHQ - 9
0-4 none
5-9 mild
10-14 moderate
15+ severe
how to classify depression for diagnosis
subclinical: less than 4 sigecap sx
mild: more than 5 sigecap sx + little functional impairment
moderate: more than 5 sigecap sx + marked functional impairment
severe: more than 5 sigecap sx + marked functional impairment +/- psychosis
treatment for mild depression
treatment for moderate - severe depression
SSRI + high intensity CBT
treatment for refractory/severe depression
ECT
give 2 subtypes/differentials for depression
seasonal affective disorder
dysthymia
what is seasonal affective disorder
recurrent
usually occurs in winter
tx is light therapy and ssri
what is dysthymia
subclinical depression for more than 2y
tx is low intensity CBT
what is IAPT referral
Improving access to Psych therapy
an NHS initiative for mild-moderate depression
2 types of self harm
cutting
head banging