schizophrenia

Question 1

what is schizophrenia

Answer 1

dissassociation from reality for at least 28 days and NOT due to substance misuse

Question 2

median age for schizo

Answer 2

25

Question 3

what is transient psychosis

Answer 3

dissasociation from reality for less than 28 days

Question 4

what lobe does shcizo most commonly affect

Answer 4

temporal

Question 5

does schizo affect males more or females

Answer 5

equal

Question 6

2 theories associated with schizo

Answer 6

1. neurodevelopment hypothesis
2. neurotransmitter hypothesis

Question 7

describe the neurodevelopment hyp[othesis

Answer 7

hypoxic ischaemic injuury or birth complications can impair brain development and increasr risk of schizo

Question 8

describe the neurotransmitter hypothesis

Answer 8

if you have increased neurotrasnmitter in mesolimbic pathway –> more positive sx

if you have decreased neurotrasnmitter in mesocortical pathway –> more negative sx

Question 9

what do positive schizo sx refer to

Answer 9

abrnormal sx that should not exist

Question 10

what do negative schizo sx refer to

Answer 10

sx that should exist but dont

Question 11

rf for scizophrenia

Answer 11

fhx - mc
smoking cannabis in youth
traumatic birth
MHI
trauma+abuse

Question 12

mc type of scizophrenai

Answer 12

paranoid shizoprehnia

characterised by persecutory delusions

Question 13

othet types of schizophrenia

Answer 13

• hebephrenic (common in young px)
• simple
• catatonic
• undifferentiated

Question 14

DVLA rules for schizophrenia

Answer 14

cant drive unless youve had 3m on treatment or good psych report

Question 15

how to catgeorise sx of schizophrenia

Answer 15

Schneider’s first-rank

Schneider’s second rank

need 1 first rank and 2 second rank to diagnose

Question 16

what are the schneider’s first rank symptoms

Answer 16

• delusional perceptions
• thought alienation
• 3rd person auditory hallucinations (voices)
• passivity (being controlled bye xternal force)

Question 17

what are the second rank symptoms

Answer 17

• non auditory hallucinations (eg visual,tactile)
• catatonia
• delusions
• decreased insight

Question 18

ddx for psychosis

Answer 18

drug induced
shizoprehnia
depression
syphillis
huntingtons
meds - steroids,cocaine, meth,LSD, ectasy

Question 19

how to diagnose schizoprehnia

Answer 19

need 1 frirst rank schneider or 2 second rank symptoms for at least 28 days

Question 20

what bloods to do for shizoprehia

Answer 20

FBC
U+E
TFT
Syphillis serology
Hba1C
B12+folate
urine
toxicology

Question 21

treatment of schizophrenia

Answer 21

trial antipsyhcotic for at least 6-8w

then try another one

last line –> clozapine

Question 22

other treatments of shizophrenia

Answer 22

CBT,CMHT,crisis team

Consider MHA 2 or 3 Section

consider social worker + care program apporach

Question 23

what is late onsent shizophrenia

Answer 23

over 45y
better prognosis
tx low dose anitpsychotics

Question 24

what is delusional disorder

Answer 24

isolated delusions for more than 3m
no loss of function
no psychosis
consider CBT

Question 25

what is shcizo affective disorder

Answer 25

shizophrenia + more than 1 mood disorder (depression or anxiety) better prognosis than schizo worse prognosis than mood disorders

Question 26

tx of schico affective disorder

Answer 26

antopsychotics + mood tx

Question 27

2 types of shcizo affective disorder

Answer 27

Schizoaffective disorder bipolar type: Schizoaffective disorder depressive type:

Question 28

describe Schizoaffective disorder bipolar type

Answer 28

Episodes of mania (extreme highs) and sometimes major depression

Question 29

describe schizoaffective disorder depressive type:

Answer 29

Only major depressive episodes