Ephedrine
Mechanism of Action:
direct and INDIRECT actions
Releases tissue stores of norepinephrine
Ephedrine
Class:
alpha/beta agonist
Ephedrine
Induction Dose: None
None
Ephedrine
Bolus Dose:
5-20mg
Ephedrine
Gtt rate: None
None
Ephedrine
Common Side Effects/ Contraindications:
Cardiac arrythmias, Hypertension, Tachycardia,
crosses BBB can result in insomnia and agitation
Ephedrine
Onset:
< 1min
Ephedrine
Peak:
2-5min
Ephedrine
Distribution half-life:
10-15min
Ephedrine
Metabolism:
Hepatic
Ephedrine
Elimination half-life/Active metabolites:
3-6hrs/
hydroxyephedrine,
p- hydroxynorephedrine, norephedrine