1
Q
Rocuronium
Mechanism of Action
A
Prevents depolarization by competitively blocking ACh from binding to nACh receptors on the motor endplate
2
Q
Rocuronium
Class
A
Nondepolarizing neuromuscular
blocking agent
3
Q
Rocuronium
Induction Dose
A
0.6 to 1.2 mg/kg
4
Q
Rocuronium
Bolus Dose
A
0.1 to 0.2 mg/kg
repeat PRN
5
Q
Rocuronium
Gtt Rate
A
5-12 mcg/kg/min
6
Q
Rocuronium
Common Side Effects/Contraindications
A
Potential to cause allergic reaction/
Hypersensitivity reactions- Anaphylaxis to Roc or other neuromuscular blocking agent
7
Q
Rocuronium
Onset
A
1-2 minutes
8
Q
Rocuronium
Peak
A
4 minutes best intubating conditions
9
Q
Rocuronium
Distribution halflife (t1/2 α)
A
30-60min
10
Q
Rocuronium
Metabolism
A
Hepatic & Renal
11
Q
Rocuronium
Elimination half-life/Active metabolites (t1/2 β)
A
1-2 hrs
Pharmacology II
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