4 Basic Types of drug action:
• Stimulation
• Depression
• Irritation
• Cytotoxicity
• Replacement
4 Mechanisms of drug action:
• Physical Action
• Chemical Action
• Enzyme mediated drug action
• Receptor mediated drug action
4 Function of receptors:
• To propagate regulatory signals from outside to within effector
• To amplify signals
• To integrate various extracellular and intracellular regulatory signals
• To adopt to short term and long-term changes with regulatory milieu and maintain homeostasis
4 Severity of drug adverse effects:
• Minor
• Moderate
• Severe
• Lethal
7 Steps Prevention of adverse effects of drugs:
• Avoid inappropriate uses
• Use correct dosage and route of the
• Consider previous history of reaction, if any
• Find out any other allergic disease existed, and take caution
• Rule out harmful interaction among drugs prescribed
• Adopt correct drug administration technique
• Carry out correct laboratory procedures to rule out reactions
4 Goals of drug therapy for ulcers:
• Neutralize existing gastric acid
• Inhibit acid secretion
• Treat infection (H. Pylori)
• Protect ulcer from further damage