How many US adults are estimated to be affected by MS
1 million
What age range does the onset of MS usually occur
20 to 50 years
Which gender is affected by MS at a rate 2 to 3 times greater
Women
What is the primary pathophysiology of Multiple Sclerosis
Demyelination of the central nervous system
Which immune cells initiate the response against myelin in MS
Autoreactive T cells
What is the most common disease course of MS
Relapsing remitting MS
Which MS course involves continuous progression from onset without plateaus
Primary progressive MS
What is the definition of Uhthoff’s phenomenon in MS context
Worsening of symptoms due to heat elevation
Which exercise testing mode is recommended for MS patients with balance issues
Cycle ergometer
Why should exercise testing for MS patients be performed earlier in the day
Fatigue generally worsens throughout the day
What scale should be used alongside HR to monitor intensity in MS patients
RPE scale
What is the most common motor disability in childhood
Cerebral palsy
What is the most common type of motor abnormality in CP patients
Spasticity
Which classification system describes functional mobility in CP patients
Gross Motor Function Classification System
What scale is used to measure spasticity in CP patients
Ashworth Scale
What HR threshold indicates maximal exertion during shuttle tests for CP patients
Greater than 180 beats per minute
Why might single-joint exercises be preferred for severe CP patients
To prevent compensation by other muscle groups
What GFR level indicates chronic kidney disease
Less than 60 mL per minute
What is the repetition maximum recommendation for strength testing in kidney disease
3-RM or higher
Why is 1-RM testing generally contraindicated for kidney disease patients
Risk of spontaneous avulsion fractures
When should exercise testing be performed for patients on maintenance hemodialysis
On nondialysis days
Which arm should be used for BP monitoring in hemodialysis patients
The arm without the arteriovenous fistula
What is the recommended initial work-to-rest ratio for CKD patients
1:1 ratio
How long should a patient wait to exercise after a dialysis treatment
2 hours