Outline 5 herniation syndromes
Define Sepsis as per SEPSIS3
Life-threatening organ dysfunction caused by a dysregulated host response to infection
What are the 3 criteria in the qSOFA?
RR >22
SBP <100
Altered mental status (GCS <14)
Define Septic Shock, as per SEPSIS3
Sepsis + vasopressors req’d to maintain
MAP >65
and
Lactate >2.0 mmol/L
after adequate fluid resuscitation
List 3 key elements of informed consent
For consent to be considered valid:
It must be voluntary
Patient must have the capacity to consent
Patient must be properly informed
List 3 key elements of decision making capacity
A patient is considered to have the capacity to consent if:
Understands the nature of the proposed investigation or treatment
Understands the anticipated effects of the proposed treatment and alternatives
Understands the consequences of refusing treatment
List 6 domains of quality in health care according to the AHQR and Institute of Medicine
Safe
Effective
Patient Centered
Timely
Efficient
Equitable
List 10 Intrinsic & 16 Extrinsic Performance-Shaping Characteristics of the ED
INTRINSIC
Limitations of human cognition
High levels of uncertainty
High decision density
High cognitive load
Narrow windows of opportunity
Multiple interruptions or distractions
Low signal-to-noise radio
Surge phenomena
Novel or Infrequently occurring conditions
Patient factors (Acuity, Language, Delirium)
EXTRINSIC
High communication load
Poor teamwork
Overcrowding
Production pressures
High ambient noise levels
Information gaps
Report delays
Inadequate staffing
Poor feedback
Inexperience
Inadequate supervision
Sleep deprivation or Sleep debt
Fatigue
Multiple transitions of care
Poorly designed procedures
ED layout
List 2 things to document if a patient wants to leave AMA
Define convergence, as it relates to mass casualties and disasters
Informal, spontaneous movement of people, messages, and supplies towards the disaster area.
Name 3 tests or things you can apply when there is a unique ethical case without precedent
1) Impartiality test
- Whether the practitioner would accept this action if he or she were in the patient’s place.
2) Universalizability test
- Whether the practitioner would be comfortable having all practitioners perform this action in all relevantly similar circumstances
3 Interpersonal justifiability test
- Whether the practitioner can supply good reasons to others for the action. Will peers, superiors, or the public be satisfied with the answers
*If the answers to the questions is affirmative, the practitioner has identified a reasonable probability that the proposed action falls within the scope of ethically acceptable actions
Name 3 situations which fulfill medical futility
Physiologic futility
Quantitative futility
Qualitative futility
Outline list of SDMs for a patient
1) Spouse (not divorced or legally separated)
2) A majority of the adult children who can be reasonably contacted
3) Parents (of an adult)
4) Domestic partner
5) Sibling
6) Close friend
7) Attending physician, in consultation with a bioethics committee
What does a p-value represent?
Probability that the observed results could have occurred due to random chance
List 15 AIDS-Defining Illnesses
INFECTIOUS:
- Multiple or Recurrent Bacterial infections
- Candidiasis of bronchi, trachea, or lungs
- Candidiasis of esophagus
- Coccidioidomycosis, disseminated or extrapulmonary
- Cryptococcosis, extrapulmonary
- Cryptosporidiosis, chronic intestinal (>1 mo duration)
- CMV disease (other than liver, spleen, or nodes), onset at age >1 mo
- CMV retinitis (w/ loss of vision)
- HSV: chronic ulcers (>1 mo duration) or bronchitis, pneumonitis, or esophagitis (onset at age >1 mo)
- Histoplasmosis, disseminated or extrapulmonary
- Isosporiasis, chronic intestinal (>1 mo duration)
- MAC, disseminated or extrapulmonary
- TB of any site, pulmonary, disseminated, or extrapulmonary
- Mycobacterium, other species or unidentified species, disseminated or extrapulmonary
- Pneumocystis jiroveci PNA
- Recurrent PNA
- Salmonella septicemia, recurrent
- CNS Toxoplasmosis, onset at age >1 mo
MALIGNANCY:
- Invasive Cervical cancer
- Burkitt Lymphoma
- Kaposi sarcoma
- Immunoblastic Lymphoma
- Primary Lymphoma of the Brain
OTHER:
- HIV related Encephalopathy
- Progressive Multifocal Leukoencephalopathy
- Wasting Syndrome 2/2 HIV
List 8 causes of ACUTE hepatic failure
ABCDs….
Acetaminophen
Hepatitis A
Autoimmune hepatitis
Amanita phalloides (mushroom poisoning)
Adenovirus
Hepatitis B
Budd-Chiari syndrome
Cryptogenic
Hepatitis C
CMV
Hepatitis D
Drugs & Toxins
Hepatitis E
EBV
Acute fatty liver of pregnancy
Reye’s syndrome
Genetic = Wilson disease
Hypoperfusion (Ischemic hepatitis, Sepsis)
HELLP syndrome
HSV
Heat stroke
Hepatectomy
Infiltration by Tumor
What is the chance of getting HIV with a needlestick from a known HIV+ patient?
0.3%
Describe situations for HAV and HBV PrEP and PEP
HAV PrEP:
- HAV Vaccine
OR
- HAV IG for nonimmune individuals who are at high risk of exposure to hepatitis A, immunocompromised patients, >6 months of age, have chronic liver disease, allergy to HAV vaccination
HAV PEP:
- ISG 0.1mL/kg IM to close personal contacts, daycare workers and kids
- ISG 0.2mL/kg IM to food-borne exposures within 2 weeks of exposure
HBV PrEP:
- HBV Vaccine (3 inj series)
HBV PEP:
- Tx w/in 1-2 weeks to prevent seroconversion
- HBIG 0.06mL/kg IM ASAP
List 4 bugs that cause a unilateral lobar PNA
S. pneumo
K. pneumo
H. flu
Morexella catarrhalis
TB
Legionella
Adenovirus
Outline DDx of a cavitary lesion seen on CXR
C → Cancer (Broncogenic, Mets)
A→ Autoimmune (GPA, RA)
V → Vascular (Septic Emboli, Pulmonary infarct)
I → Infectious (MSSA/MRSA, TB, Klebsiella, MAC, Aspergillus, anaerobes)
T→ Trauma (Pneumatocele)
Y→ Youth (CPAM, Bronchogenic cysts)
Outline CURB-65 rule
Risk of 30-day mortality
0 = 0.7%
2 = 9.2%
5 = 57%
0-1 = outpt mgmt
2 = inpt mgmt
3+ = consider ICU
Outline the PECARN CT Head Rule
<2 YEARS:
CT if:
* Altered
* GCS <15
* Palpable skull fracture
Observe if:
* Severe mechanism
* LOC >5s
* Non-frontal scalp hematoma
* AbN behaviour as per parents
Otherwise no CT
> 2 YEARS:
CT if:
* Altered
* GCS <15
* Basilar skull fracture
Observe if:
* Severe mechanism
* LOC
* Severe headache
* Vomiting
Otherwise no CT
Outline the 4 severe mechanisms of injury in the PECARN CT Head Rule
Struck by high impact object
MVC with fatality, ejection, or rollover
Pedestrian or Bike w/out helmet vs MV
Fall from >3ft (Age <2) or >5ft (Age >2)
Outline Inclusion (2) & Exclusion (4) criteria for PECARN CT Head Rule
INCLUSION
1) Blunt Head trauma <24hr ago
2) Age <18
EXCLUSION
1) GCS <14
2) Previous neurologic disorder
3) Trivial injury mechanism
4) Penetrating head trauma
5) Known brain tumour