What 3 etiologies can precipitate thought d/o symptoms?
Psychiatric
Medical
Toxicologic
What is male and female age of onset for schizophrenia?
Male = 18-25 yrs
Female = 25-35 yrs
What are 4 social factors that have higher risks for developing schizophrenia?
List 7 factors w/ increased influence on risk of developing schizophrenia
List 6 positive and 3 negative symptoms of psychosis
Positive:
- delusions
- hallucinations
- abnormal motor behaviour
- disorganized speech
- disorganized thought
- disorganized attention
Negative:
- catatonia
- decreased motivation
- diminished expressiveness
- cognitive deficits: impaired executive functions, memory, speed of mental processing
List 5 types of hallucinations
auditory
olfactory
visual
gustatory
somatic
How do you treat catatonia?
Benzodiazepines
Describe the 3 developmental phases of schizophrenia
1) Premorbid
- development of negative symptoms with deterioration in personal, social, and intellectual functioning
2) Progressive
- precipitated by a stressful life event precipitating the development of positive symptoms
*usually when pts are brought to ED
3) Residual
- persistence of progressive symptoms and disability
List 12 Medical Disorders That May Cause Acute Psychosis
Metabolic Disorders:
- HypoNa
- HyperCa
- Hypoxia
- Hypercarbia
- Hypoglycemia
Inflammatory Disorders:
- Sarcoidosis
- Anti-NMDA receptor encephalitis
- SLE
- Giant cell arteritis
Organ Failure:
- HE
- Uremia
Neurologic Disorders:
- Alzheimers
- Parkinsons
- Huntingtons
- CVA
- Encephalitis (including HIV)
- Encephalopathies
- Epilepsy
- MS
- Neoplasms
- Normal-pressure hydrocephalus
- Pick disease
- Wilson disease
Endocrine Disorders:
- Addison disease
- Cushing disease
- Panhypopituitarism
- Parathyroid disease
- Postpartum psychosis
- Recurrent menstrual psychosis
- Sydenham chorea
- Thyroid disease
Deficiency States:
- Niacin
- Thiamine
- Vitamin B12
- Folate
List 10 Pharmacologic Agents That May Cause Acute Psychosis
Antianxiety Agents:
- Alprazolam
- Diazepam
- Clonazepam
- Chlordiazepoxide
- Clorazepate
- Ethchlorvynol
Antibiotics:
- Isoniazid
- Rifampin
Anticonvulsants:
- Phenobarbital
- Phenytoin
- Primidone
- Ethosuximide
Antidepressants:
- Amitriptyline
- Doxepin
- Imipramine
- Protriptyline
- Trimipramine
Cardiovascular Drugs:
- Procainamide
- Propranolol
- Captopril
- Digitalis
- Disopyramide
- Methyldopa
- Reserpine
Drugs of Abuse:
- Alcohol
- Amphetamines
- Cannabis
- Cocaine
- LSD
- Psilocybin
- Opioids
- Phencyclidine (PCP)
- Sedative-hypnotics
Miscellaneous Drugs:
- Antihistamines
- Anti-neoplastics (Chemo)
- Bromides
- Cimetidine
- Corticosteroids
- Disulfiram
- Heavy metals
Outline the DSM-5 Diagnostic Criteria for Schizophrenia
A. 2 or more of the following:
- must each be present for significant portion of 1mo period
- at least one must be (1), (2), or (3)
B. Markedly decreased level of functioning in 1 or more major areas since onset of abnormal behaviour:
- work
- interpersonal relations
- self-care
C. Continuous disturbance persist for at least 6mo
- must include at least 1mo of symptoms in Criterion A
- disturbance may be manifested by negative symptoms or by 2+ symptoms listed in Criterion A present in an attenuated form
D. Schizoaffective, Depressive, Bipolar d/os with psychotic features are ruled out
E. Disturbance is not attributable to a substance or medical condition
F. If hx of ASD or a communication d/o of childhood onset, the additional diagnosis of schizophrenia is made only if prominent delusions or hallucinations, in addition to the other required symptoms of schizophrenia, are also present for at least 1mo
List dx of psychotic disorder based on time duration
Brief Psychotic D/O = <1mo
Schizoaffective D/O = >2 weeks of symptoms w/out prominent mood episodes
Schizophreniform D/O = 1-6mos
Clinical Schizophrenia = >6mo
What is Delusional D/O?
List 6 risk factors for violence in patients with schizophrenia
List 3 risk factors predicting the need for restraint or seclusion in the ED
List common drugs for sedation in a psych pt
What is the titration goal for sedation in a psych pt?
= Induction of rousable sleep
*NOT unconsciousness
List 4 adverse events associated w/ benzo use for sedation
Which psychiatric patients should be hospitalized? (4)
What 5 factors place psychiatric pts at higher risk for ED recidivism?
List 5 examples of Somatic Symptom and Related Disorders
Define Somatic Symptom Disorder (SSD)
Define Illness Anxiety Disorder (IAD)
“Hypochondriasis”
Define Conversion Disorder
“functional neurologic symptom disorder”