Infection & Immunity 2 > Helicobacter > Flashcards

Helicobacter Flashcards

(19 cards)

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1
Q

Yr first observed & in what part of body

A

1983; stomachs of type B gastritis patients

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2
Q

Former name of helicobacter

A

Campylobacter pyloridis

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3
Q

3 important human pathogens

A
  • H. Pylori (No animal reserve)
  • H. Cinaedi (humans & rodents)
  • H. Fenneliae (human & rodents)
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4
Q

Characteristics

A
  • gram -ve
  • spiral, s-shape; sometimes rods
  • corkscrew motility
  • microaerophilic
  • multiple flagella
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5
Q

Why are their multiple flagella so important

A
  • virulence factor
  • help w/ burrowing, resisting acidic envir., and urease
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6
Q

Best growing conditions

A
  • blood & chocolate agar
  • after incubation for 2-5 days
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7
Q

What type of motility is seen in Helicobacter?

A

Corkscrew motility

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8
Q

Why is helicobacter so important?

A
  • most reported species in human GIT infections
  • zoonotic
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9
Q

Which species is Helicobacter most important in?

A

Dogs and cats

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10
Q

Main characteristic differences between campylobacter and helicobacter?

A
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11
Q

Characteristics of H. Pylori

A
  • gram -ve
  • Spiral and rod shaped
  • corkscrew motility
  • multiple flagella
  • virulence factors
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12
Q

List the virulence factors of H. Pylori

A
  • multiple flagella (burrowing)
  • can live in extreme acidity
  • enzyme urease (weakens acidity)
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13
Q

H. Pylori affects

A

Humans

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14
Q

H. Canis, H. Felis, H. Heilmannii, and H bizzozeronii affect

A

Dogs and cats

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15
Q

Symptoms of helicobacter infection in animals

A
  • vomiting
  • dehydration
  • poor appetite
  • bowel sounds
  • abdominal pain
  • diarrhea
  • weakness
  • sudden death
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16
Q

4 ways to test for Helicobacter infection

Study These Flashcards
A
  • endoscopic and gastric biopsy
  • stool antigen test
  • stool PCR test
  • Urea breath test
17
Q

Stool antigen test

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A
  • most common to detect H. Pylori
  • looks for antigens assc. W/ H. Pylori infection
18
Q

Urea breath test

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A
  • gold standard test in diagnosing H. Pylori
19
Q

Treatment for helicobacter infections

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A
  • recommended antibiotics: amoxicillin, tetracycline, metronidazole, bismuth subsalicylate
  • proton-pump inhibitors (omeprazole)
  • H2-receptor blockers (famotidine)

(All for 2-3 weeks)

Infection & Immunity 2
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