ain function is to transport oxygen from the lungs to tissues and transport carbon dioxide from the tissues to the lungs for exhalation
Hemoglobin
1 hema is
1 moles of oxygen
1 Hb means
4 moles of oxygen
involves the binding, inactivation, and transport of nitric oxide. Nitric oxide is secreted by vascular endothelial cells and causes relaxation of vascular wall smooth muscle and vasodilation.
Hemoglobin
Ref values for hemoglobin in children
12 to 15 g/dl
Adult male hemoglobin
14 -18
Adult female hemoglobin
12- 15 g/dl
Refers to the amino acid sequence of the polypeptide chains
Primary structure of hemoglobin
Refers to the arrangement of the helices into a pretzel-like configuration
Tertiary structure of hemoglobin
Refers to chain arrangements in helices and non-helices.
Secondary structure of hemoglobin
The complete hemoglobin molecule structure
Quarternary structure
1 hemoglobin is composed of
4 heme
Two dimers ( 2 alpha and 2 beta)
1 RBC can carry
4 molecules of oxygen
1 heme molecule
4pyrrole rings
1 heme molecule means
1 ferrous iron
Heme synthesis occurs in
Mitochondria and normoblast
Heme is dependent in
Glycine
Succinylcholine
Coenzyme A
Aminolevunilic
Vitamin b6
Goo in synthesis occurs in
Ribosome
What chromosome is for alpha and zeta
16
first stage of hemoglobin synthesis
Rubricyte
last stage capable of hemoglobin synthesis
Reticuloycte