Total volume
Increased
Total leukocytes
Increase
Immature RBC
Increased
Platelets
Increased
LAP stain
Increased
ESr
Decreased
Serum iron
ESR
Erythropoietin
Decreased or absent
Blood histamine
Increased
Unsaturated b12 binding capacity
Increased
Basophil count
Increased
Hyperuricemia
Present or absent
Hyperuricosunuria
Present or absent
MAJOR DIAGNOSTIC CRITERIA FOR POLYCYTHEMIA VERA
1. Hemoglobin >18.5 g/dL in males, 16.5 g/dL in females or other evidence of increased red cell volume
True
MAJOR DIAGNOSTIC CRITERIA FOR POLYCYTHEMIA VERA
Presence of JAK2V617F or other functionally similar mutations (e.g., JAK2 exon 12 mutation)
True
MINOR DIAGNOSTIC CRITERIA FOR POLYCYTHEMIA VERA
1. Hypercellular bone marrow with prominent granulocytic, erythrocytic, and megakaryocytic proliferation
True
MINOR DIAGNOSTIC CRITERIA FOR POLYCYTHEMIA VERA
Decreases serum erythropoietin levels
3. Endogenous erythroid colony formation in vitro
True