Red Cell Abnormalities

Question 1

Refers to the Variation of RBC size

Answer 1

Anisocytosis

Question 2

Assess anisocytosis. Increased in heterogenous population of cells. It is the coefficient of variation of RBC volume expressed as percentage
♥ Computed by dividing the SD by the mean of the RBC size distribution

Answer 2

RDW distribution

Question 3

Formula of RDW

Answer 3

Sd/ mean x 100

Question 4

Normocytic RBC composition

Answer 4

Normal RBc size 6-8 um
Nomal MCV 80-100

Question 5

Microcytic RBC component

Answer 5

Less than < 6 um in size
Less than 80 fl MCV

Question 7

Microcytic RBc

Answer 7

Larger than 9um in size
Greater than 100 fl in MC

Question 8

Refers to the Variation in hemoglobin content

Answer 8

Anisochromia

Question 9

Normochromic composition

Answer 9

Normal amount of hemoglobin
Normal RBC have central pallor
MCHC= 32-36 %

Question 10

Hypochromic composition

Answer 10

Central pallor area exceeds at 1/3 diameter of the cell
Decrease MCHC < 32 %

Question 11

Hyper chronic/ spherocyte composition

Answer 11

No central pallor
Increase MCHC
Spherocytosis

Question 12

Polychromatic/ Reticulocyte sis / polychromatophilia composition

Answer 12

Immature young RBC
Blue green discoloration
Increase erythropoeitic activity

Question 13

Refers to the variation of RBC cell shape

Answer 13

Poiklocytosis

Question 16

Other names for a Acanthocyte

Answer 16

Spur cells

Thorn cells

Question 17

Spheroid with 3-12 irregular spikes/ spicules
Abnormal ratios of membrane lecithin and sphingomyelins

Answer 17

Acanthocytes
Spur cells
Thorn cells