hepatitis
inflammation of the liver & is caused by viral/bacterial sources or chemical damag
HAV mode of transmission
found in water & food, common in crowded living condition; fecal oral transmission, incubates in 2-6 weeks
HBV mode of transmission
those exposed to needle punctures, blood products, & those engaging in unprotected sex; iv users have highest incidence, incubates 6wks-6 months
HCV mode of transmission
is transmitted through blood or blood products; leading cause of poor transfusion hepatitis, incubation 5-10wks
pathophysiology
-the liver performs metabolic & regulatory functions & decreased functioning of the liver is the presenting symptom
-complete regeneration of the liver can occur even when 70% of liver cells are destroyed
risk factors
-hav; day care centers, group homes, foreign travels
-hbv; iv drug users, healthcare workers, dialysis pts, multiple sexual partners
-hcv; frequent blood transfusions, male intercourse, iv drug users, hospital healthcare workers
subjective nursing assessment
-fever
-malaise
-nausea & vomiting
-anorexia
-abdominal pain
-headache
-joint pain
objective nursing assessment
-jaundice, but not always present
-dark urine
-clay colored stools
-hepatosplenomegally
-rash in hpv
diag studies
-liver biopsy in chronic disease
-screenings for lfts, increased alt & ast, antibody tests, cbc, & u/a
tx & prognosis hep a
-pts can be sick a few weeks to a few months
-most recover w no liver damage, severe damage, & death is rare
inactivated hep a serum
prevention for those who expect to be exposed such as daycare providers, & international travelers
immunoglobin
for close contacts in an endemic of hav
tx & prognosis hep b
-15-25% w chronic disease develop chronic liver disease, cirrhosis, liver failure, or liver cancer
-acute tx; none, supportive care only
-chronic tx; monitor for disease progression, antiviral drugs may work for some, prophylaxis or hbv vaccine for pats @ risk
tx & prognosis hep c
-more than 50% of those infected w hcv develop chronic infection
-no recommended tx for acute hcv
-if disease becomes chronic there are several meds avaliable which usually involves 8-12 weeks for oral therapy, the meds have a good prognosis for over 90% w few side effects