SLE
chronic inflammatory autoimmune disease that affects multiple body systems
premature causes of death associated w SLE
-active disease
-organ failure
-infection
-cardiovascular disease from accelerated atherlosclerosis
s/s
caused by trapping of antibody/antigen complexes in capillaries & visceral structures, & autoantibody-mediated destruction of host cells
-fatigue
-muscle/joint pain
-butterfly rash
-hair loss
-fever
-mouth sores
-proteinuria
risk factors
-woc between 15-44 are @ highest risk of lupus
-african americans, hispanics/latinos, asian americans, & native populations @ higher risk
-uv light
-smoking
-epstein-barr virus
-occupational exposure to silica
-genetic predisposition
85% of patients w SLE are;
women
drugs that may cause exacerbations
-sulfanamides
-PCN
-hydralazine
-OCP’s
pregnancy & newborns
-includes periods of flares & remission, more common in pregnancy
-increased risk of fetal loss
-newborn risk of arrythmias
subjective nursing assessment
-fatigue, myalgias, flu like symptoms
-dyspnea, hemoptysis
-headaches, neuropathies
-photophobia, abdominal pain
-raynauds phenomenon in ab 20% of cases
objective nursing assessment
-butterfly rash on cheeks
-pericardial friction rub, cardiac arrythmias
-edema