Types and causes?
Primary - conns ( adrenal adenoma)
Idiopathic
Familial
BL adrenal hyperplasia (mainly men)
Secondary- chronic low bp secrecting hogh levels of renin
Clinical features?
Htn Hypokalemia Matabolic alkalosis Non specific symptoms Muscle weaknesses,nocturia,tetany,constipationarrhythmias
Ix?
1.Iry- aldosterone high renin low
IIry- high aldosterone high renin
2.hypokalemia
3.urinary Kc loss
Tx?
1.Adenoma sx removal
2.hyperplasia-
Aldosterone antagonist-spironolactone
Aldosterone receptor antagonist- eplerenone