IMN

Question 1

Infection and IP

Answer 1

EBV 1-2 months

Question 2

Clinical features?

Answer 2

Fever 
Headache 
Malaise 
Sore throat 
Palatal petechiae and transient macula rash (ampicillin) 
Cervical lymphadenopathy (esp pos) 
Splenomegaly/rupture 
Mild hep/jaundice 
Hemolytic anemia secondary to cold agglutinins IGM 
Myocarditis 
Meningitis 
Encephalitis 
Mesentric adenitis 
Tonsilar obstruction 
Burkitt’s lymphoma
Nasopharyngeal ca

Question 3

Dx?

Answer 3

Atypical mononuclear test (activated CD8+ T cells)

Confirm - heterophil Ab test in 2nd w ( mono spot test) - detects IgM Ab