PHARMA I > HYPNOTICS > Flashcards

HYPNOTICS Flashcards

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1
Q

aka?

*for insomnia

A

nonbenzodiazepine receptor agonists

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2
Q

what receptor is activated?

effect?

NBBRAs cons?

A

BZ2 receptor

enhanced activity of GABA with hypnosedative and amnesic effects (induces CNS depression)

sleep walking and activities

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3
Q

Black Box warning – complex sleep behavior

A

Zolipdem

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4
Q

these put you to sleep?

A

Zolipdem
Zalepion
Eszopiclone

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5
Q

misc agents for insomnia?

A

ramelteon

suvorenxant

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6
Q

name this misc agents for insomnia?

melatonin receptor agonist
-no effect on GABA or BZD receptor so no risk of dependence

A

Ramelteon

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7
Q

name this misc agents for insomnia?

Orexin*** receptor antagonist

  • Contraindicated in narcolepsy
  • -since the orexin receptor has been indicated in narcolepsy

–Adverse Effects = sleep paralysis, cataplexy symptoms

A

Suvorexant

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8
Q

what are Orexin?

A

wake promoting neuropeptides

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