immune system Flashcards

(26 cards)

1
Q

innate immunity

A
  • non specific
  • born with it
  • physical Barries like skin and mucous membranes
  • chemical barriers like acid stomach pH, enzymes like lysozyme
  • cellular defenses like phagocytes, natural killer cells
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2
Q

adaptive immunity

A
  • when your first exposed to an antigen, your body learns it and makes a specific response
  • next time you see it, MUCH faster response
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3
Q

adaptive immunity involves lymphocytes

A

T cells
- mature in thymus
- handle cell mediated immunity (kill infected cells)
B cells
- mature in bone marrow
- handle humoral immunity (make antibodies)

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4
Q

T cells

A
  1. helper T cells
  2. Cytotoxic (killer) T cells
  3. Memory T cells
  4. regulatory T cells
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5
Q

helper T cells

A
  • activate other immune cells
  • needed for activating B cells and cytotoxic T cells
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6
Q

Cytotoxic (killer) T cells

A
  • destroy infected or abnormal cells
  • release enzymes to kill them
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7
Q

memory T cells

A
  • remember the antigen
  • respond quickly on second exposure
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8
Q

regulatory T cells

A
  • prevent the immune system from attacking your own body
  • help stop the response when the infection is gone
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9
Q

B cells

A
  1. plasma cells
  2. memory B cells
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10
Q

plasma cells

A

make and release antibodies

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11
Q

memory B cells

A
  • remember the antigen
  • produce antibodies quickly during the next infection
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12
Q

innate immune system cells

A
  1. neutrophils
  2. macrophages
  3. monocytes
  4. NK cells
  5. eosinophils
  6. basophils
  7. mast cells
  8. dendritic cells
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13
Q

neutrophils

A
  • most common WBC
  • first responders
  • eat bacteria
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14
Q

macrophages

A
  • big phagocytes
  • eat pathogens and dead cells
  • present antigens to T cells
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15
Q

monocytes

A
  • become macrophages when they enter tissues
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16
Q

NK cells

A
  • kill virus infected cells and cancer cells
17
Q

eosinophils

A
  • fight parasites
  • help with allergies
18
Q

basophils

A
  • release histamine during allergic reactions
19
Q

mast cells

A
  • similar to basophils
  • found in tissues and basophils are found in blood
  • release histamine - inflammation
20
Q

dendritic cells

A
  • antigen presenting cells
  • bridge between innate and adaptive immunity
  • activate T cells
  • scout antigens and show them to T cells
21
Q

major tissues for immune function

A
  1. bone marrow
  2. thymus
  3. spleen
  4. lymph nodes
  5. MALT
22
Q

bone marrow

A
  • this is where all blood cells are made, including immune cells
  • it is also where B cells mature
  • bone marrow = birthplace + B cell training center
23
Q

thymus

A
  • located above the heart
  • this is where T cells mature
  • shrinks in adulthood
24
Q

spleen

A
  • filters old red blood cells
  • contains many macrophages and lymphocytes
  • helps clean pathogens from blood
  • spleen = blood filter + immune cell storage
25
lymph nodes
- small bean shaped filters located throughout the body - trap pathogens, toxins and cancer cells - give lymphocytes a place to multiply - lymph nodes = pathogen checkpoints
26
MALT (Mucosa associated lymphoid tissue)
- found in mucus membranes (tonsils, appendix, peyers patches) - exposed to things you swallow or inhale