Lecture 1

Question 1

prion cell structure

Answer 1

Not cellular, proteinaceous

Question 2

prion nucleic acid

Answer 2

None

Question 3

prion lifestyle

Answer 3

Not alive

Question 4

prion size

Answer 4

Large protein

Question 5

prion example

Answer 5

PrpSC

Question 6

virus cellular structure

Answer 6

Not cellular

Question 7

virus nucleic acid

Answer 7

DNA or RNA

Question 8

virus lifestyle

Answer 8

Obligate intracellular organism

Question 9

virus size

Answer 9

Seen by electron microscopy

Question 10

virus examples

Answer 10

Hep B, HIV

Question 11

bacteria cellular structure

Answer 11

Prokaryotes

Question 12

bacteria nucleic acid

Answer 12

Both DNA & RNA

Question 13

bacteria lifestyle

Answer 13

Usually free, but sometimes intracellular

Question 14

bacteria size

Answer 14

Seen by light microscopy

Question 15

bactria examples

Answer 15

• m.tuberculosis
• s.aureus
• e.coli

Question 16

fungi broad examples

Answer 16

Moulds and yeasts

Question 17

fungi cellular structure

Answer 17

Eukaryotes

Question 18

fungi nucleic acid

Answer 18

Both DNA & RNA

Question 19

fungi lifestyle

Answer 19

Usually free living, may be intracellular

Question 20

fungi size

Answer 20

Seen by light microscopy

Question 21

fngi examples

Answer 21

Aspergillus, candida

Question 22

single-celled parasites (protozoa) cellular structure

Answer 22

Eukaryotes

Question 23

protozoa nucleic acid

Answer 23

Both DNA & RNA

Question 24

protozoa lifestyle

Answer 24

Usually free living, maybe intracellular

Question 25

protozoa size

Answer 25

Seen by light microscopy

Question 26

protozoa examples

Answer 26

Plasmodium, trypansoma

Question 27

metazoa cellular structure

Answer 27

Eukaryotes

Question 28

metazoa nucleic aicd

Answer 28

Both DNA & RNA

Question 29

metazoa lifestyle

Answer 29

Free-living

Question 30

metazoa size

Answer 30

Seen by light microscopy or naked eye

Question 31

metazoa examples

Answer 31

Schistosoma, ascaris

Question 32

salmonella typhi is an example of ?

Answer 32

Bacteria

Question 33

fungi yeast example

Answer 33

Candida

Question 34

fungi mould example

Answer 34

Aspergillus

Question 35

plasmodium falciparum is an example of?

Answer 35

Protozoa

Question 36

ascaris lumbricoide worms are visible with

Answer 36

Naked eye

Question 37

ascaris lumbricoide eggs are visible with

Answer 37

Microscope

Question 38

what is the universal phylogenetic tree based on ?

Answer 38

evolutionary relationship based on rna sequence comparison

Question 39

which two microbial agents don't have rna?

Answer 39

virus & prions

Question 40

which microbial agent is prokaryotic?

Answer 40

bacteria

Question 41

which microbial agent is eukaryotic?

Answer 41

1. fungi 2. protozoa 3. metazoa

Question 42

2 examples of metazoa?

Answer 42

1. helminth worms 2. ectoparasites

Question 43

2 conformer states of prions

Answer 43

normal conformer & rogue conformer

Question 44

example of normal conformer prion?

Answer 44

prpc - normal endogenous protein

Question 45

example of rogue conformer prion?

Answer 45

prpsc - abnormal scrapie protein

Question 46

what does it mean when virus has a lifestyle as 'obligate intracellular organism?'

Answer 46

virus requires a host cell to replicate, metabolise and survive

Question 47

which parasite is plasmodium falciparum?

Answer 47

malaria parasite

Question 48

2 functions of teichoic acid in the gram positive cell envelope?

Answer 48

1. adhesion of bacteria to host cell 2. inflammatory response in host

Question 49

petidoglycan/cell wall function

Answer 49

1. maintain cell shape 2. protect against osmotic lysis

Question 50

effect of beta-lactam penicilin on peptidoglycan?

Answer 50

prevents cross linking of the peptide side chains

Question 51

effect of lysozyme on peptidoglycan?

Answer 51

breaks the nam-nag bonds

Question 52

function of lipopolysaccharides?

Answer 52

causes clinical effect of gram -ve infection

Question 53

what does lipopolysaccharide a cause?

Answer 53

fever, septic shock, death

Question 54

2 functions of capsule/slime layer

Answer 54

1. adhesion 2. helps bacteria avoid phagocytosis

Question 55

which 2 bacteria are endospores formed in?

Answer 55

clostridium & bacillus