What are the three main components of the lymphatic system?
Lymphatic vessels, lymphatic organs, and lymph nodes
What is lymph?
Clear fluid that arises from filtration of blood from arterial part of capillaries into interstitial spaces
What happens to filtered blood in interstitial spaces?
Majority is directly reabsorbed into blood vessels; remaining is left in interstitial space, collected by lymphatics and redirected into venous system
Where does lymph collected by lymphatic vessels drain?
Into the vena cava superior
Lymphatic System: Function related to small intestine
Absorb fat from small intestine into lymphatic lacteals
Lymphatic System: Function related to tissue fluid
Drain excess tissue fluid, hormones, and plasma proteins and return them to circulatory system (not all fluid returns to bloodstream - extra enters lymphatic vessels)
Lymphatic System: Function related to immune response
Protect body against infection by activating defense mechanism; responds to eliminate pathogens from body
What is the role of lymphocytes in the lymphatic system?
Production, maintenance, and distribution of lymphocytes that provide defense against infections (pathogens), abnormal body cells, and foreign proteins
Where are protective cells of the lymphatic system found?
Throughout bloodstream, in lymphatic organs, and can migrate into tissues
What are the alternative names for the lymphatic system?
Lymphoid system or Immune system
What are the components of the lymphatic system network?
Lymphatic capillaries, Lymphatic vessels, Primary and secondary lymphoid organs including lymph nodes
Where does the lymphatic system begin?
In the periphery of the body with lymphatic capillaries that collect lymph
What do lymphatic capillaries give during their course?
Bigger lymphatic vessels
What are the two large lymphatic trunks that lymph flows into?
Thoracic duct (on left) and Right lymphatic duct (on right)
List the 5 components of the Lymphatic System
1) Lymph 2) Lymphocytes 3) Lymphatic vessels 4) Lymphoid organs 5) Lymph nodes
What is lymph in relation to tissue fluid?
Tissue fluid that has entered the lymphatic vessels (excess tissue fluid)
What are the two functions of lymph?
1) Transports proteins and other molecules to bloodstream 2) Moves foreign particles to lymph nodes
What is the normal appearance of lymph?
Usually clear, colorless fluid, similar to blood plasma but low in protein
How does composition of lymph vary?
Varies from place to place; after a meal, lymph from small intestine has milky appearance due to lipid content
What may lymph contain?
Macrophages, viruses, bacteria, cellular debris, and even traveling cancer cells
What are the two broad categories of lymphatic structures?
A. Lymphatic vessels B. Lymphoid tissues/organs
What are the primary (central) lymphoid organs?
Bone marrow and thymus
What are the secondary (peripheral) lymphoid organs?
Lymph nodes, spleen, mucosal (MALT)
How are lymphatic vessels similar to veins?
Similar structure - thin with valves