lymphatic system Flashcards

(60 cards)

1
Q

What is lymph?

A

a clear watery liquid that is formed from interstitial (btwn tissues) fluid

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2
Q

What percent of interstitial fluid diffues into capillaries vs lymphatic vessels?

A

90% to capillaries

10% to the lymphatic vessels

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3
Q

What are lymph “dead ends”

A

lymph vessels have “dead ends” that gp tp lymph capillaries

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4
Q

What prevents lymph from flowing backwards?

A

Lymph vessels are lined with overlapping epithelial cells and have internal valves.

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5
Q

Where do lymph vessels carry lymph

A

to lymph nodes

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6
Q

unlike lymph vessels, lymph nodes are surrounded by what?

A

a capsule of connective tissue

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7
Q

What forms the structure of the lymph node?

A

Trabeculae made of reticular fibers

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8
Q

Inside lymph nodes, what are germinal centers?

A

Germinal centers are areas of rapid mitosis where lymphocytes and macrophages are produced quickly to fight infection

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9
Q

Lymph nodes filter the lymph and send it through what?

A

an efferent vessel

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10
Q

What are the two ducts in the chest that filtered lymph is eventually delivered to?

A

-right lymphatic duct
-thoracic duct

these ducts merge with veins where fluid re-enters the circulatory system

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11
Q

What does MALT stand for

A

mucosa associated lymphoid tissues

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12
Q

Are lymph nodules surrounded by a capsule

A

No

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13
Q

What do tonsils do

A

Form a protective ring around the throat to keep foreign invaders from entering the nose and mouth

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14
Q

What do the peyers patches and appendix do

A

they are groups of lymphocytes near the small intestine that filter bacteria from food and keep beneficial bacteria in the small intestine

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15
Q

What does the thymus do

A

-it is part of the endocrine and lymphatic system
-it produces thymosin (causes T lymphocytes maturation)
-T lymphocytes come here from bone marrow for thymic education

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16
Q

What does the spleen do

A

contains 2 types of tissues
-white pulp - filters blood
-red pulp - removes worn-out rbc and is a storage reservoir for blood

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17
Q

What is lymph made of

A

Water and WBC

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18
Q

What is the function of the lymphatic system

A

transports, filters, and cleans body fluids of pathogens, toxins and other unwanted substances

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19
Q

What are the extracellular body fluids

A

-plasma in the bloodstream
-interstitial fluid in tissues
-lymph in lymphatic vessels and nodes

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20
Q

Lymphatic vessels pick up excess ___ fluid, route it through lymph nodes for ___ and return it to the bloodstream

A

-interstitial
-filtering

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21
Q

Facts about lymph nodes

A

-100’s throughout body
-vary in size up to 2.5 cm
-filter lymph
-site of lymphocyte production

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21
Q

what is metastasis

A

occurs when cancer spreads to a new location in the body away from its original site; often occurs through the lymphatic system

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22
Q

What is true and not true about the flow of lymph?

A

True:
-always moves twrd the heart
-returned to the venous system through ducts
-valves keep it flowing in one direction

false:
-nodes act as pumps to keep fluid moving

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23
Q

what are the 2 types of WBC found in lymph nodes

A

-macrophages engulf & destroy foreign particles

-lymphocytes monitor fluid for antigens and trigger an immune response

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24
What does the thymus produce in children
lymphocytes
25
What is the difference btwn specific and nonspecific defenses of the immune system
the protect the body from all foreign invaders regardless of their type or location
25
name 2 mechanical barriers to the body that comprise the 1st line of defense
skin and mucous membranes
26
how does the skin offer both physical and chemical barriers to pathogens
physical: unbroken epidermis keeps out microbes chemical: bacterial growth inhibited by acidic sweat; sebum contains antibacterial substances
27
how does cilla contribute to nonspecific defenses
cilia found on some mucous membranes sweep away foreign particles
27
what is the immune function of phagocytic cells
engulf foreign particles and destroy them
28
what are the 5 symptoms of an inflammatory response
1. redness 2. heat 3. swelling 4. pain 5. loss of function
28
What kind of lymphocyte binds to and kills certain tumor cells and virus infected cells
Natural Killer (NK) cells
29
What triggers an inflammatory response
tissue damage
30
What is interferon
secreted by virus-infected cells to protect nearby cells
30
what effect do inflammatory chemicals have on blood vessels
blood vessels dilate and capillaries become leaky
31
What are complement proteins
attach to foreign cells to tag them for destruction by phagocytes
32
What is perforin
produced by NK cells to create holes in plasma membranes of infected cells
33
What is a histamine
produced by damaged cells to trigger inflammatory response
34
What is diapedesis
the movement of white blood cells from capillaries into tissues
35
what are 2 benefits of a fever
1) limits the ability of bacteria to multiply 2) speeds up metabolic processes such as tissue repair
36
what are characteristics of the immune system
-antigen-specific -systemic -has memory
37
What are the 2 divisions of the immune system
-humoral, or antibody-mediated immunity -cellular, or cell-mediated immunity
38
what is an antigen
Any substance that triggers an immune response
39
what is an antibody
A protein produced by B cells with a unique shape that is specific to one type of antigen
40
what are the two main cell populations that provide immunity
lymphocytes and macrophages
41
facts abt T cells?
-non-antibody producing lymphocytes -function in cell-mediated immunity -develop in the thymus gland
42
What are the types of immunity
Acquired Active immunity: infection or vaccination Acquired Passive immunity: antibodies from mother or doner Memory active immunity: provides immunological memory memory passive immunity: no memory
42
facts abt b cells?
-produce antibodies -function in humoral immunity -develop in bone marrow
42
What are the parts of an antibody
a) variable portion b) heavy chain c) light chain d) constant portion
43
What is the humoral immune response
-activated when B cell antibodies bind to antigens on the surface of a -activated B cells produce a large number of -Most clones will develop into cells which will produce antibodies for a few weeks or months -some clones develop into B cells that will provide a swift and effective secondary response
43
how do macrophages play a role in nonspecific and specific immunity
nonspecific: engulf foreign particles specific: bear the proteins of ingested particles on their plasma membrane to attract T cells
44
How do vaccines provide immunity
they stimulate a primary immune response so that immunity is provided in case of a second exposure to the pathogen
45
What do both cytotoxic T cells and helper T cells develop from?
Lymphocytes
46
What is aids?
AIDS is acquired immune deficiency syndrome -viral disease weakens immune system by infecting helper T cells -caused by HIV virus
47
What is an autoimmune disease and name examples
When the immune system attacks "self" antigens, resulting disease is an autoimmune disease Ex: multiple sclerosis, Type I diabetes, lupus, rheumatoid arthritis
48
What kind of recognition does T cell activation require?
Double recognition: bind with an antigen and a macrophage
49
T cell clones either ____ infected cells or develop into ____ T cells
Destroy, Memory
50
What type of T cells directly attack infected cells or cancer cells?
Cytotoxic T cells
51
What type of T cells circulate through the body and stimulate other immune cells into action?
Helper T cells
52
where are the major parts of the lymph tissue located?
Bone marrow Spleen thymus gland lymph nodes tonsils