roles of membranes in cells
structure of plasma membrane
made of double layer of phospholipids
- large and charged molecules cannot pass through the phospholipid bilayer e.g. glucose, ions (NA+, CL-)
- can pass = co2 or 02
hydrophilic head and hydrophobic tail
fluid model mosaic
effect of saturated fats on membrane fluidity -o-
effect of unsaturated fats on membrane fluidity -o-
Membranes are less fluid
bends are less tight= membranes are more fluid
How cholesterol affects membrane fluidity
If it too hot or cold how does cholesterol react ?
cholesterol affect heart health and associated with heart attacks
Too hot = cholesterol interacts with fatty acid, stopping them from pulling apart. Membrane doesn’t become too fluid
Too cold = cholesterol stops fatty acid tails from packing too tightly - membranes remains fluid
endothelial cells in blood vessels
- primary function
- roles
the primary function of endothelial cells is to form a smooth non stick surface that allows blood to flow freely
they play a crucial role in
- regulating blood vessel tone which affects blood pressure ( Vasodilation lumen gets wider and vasoconstriction lumen gets narrower )
- immune response
- the exchange of substances between the blood and surrounding tissues
Define cell signalling
A molecule from one cell binds to another cell leading to a response .
Insulin ( from pancreas ) -> receptors ( muscle and liver)
receptors are usually glycoproteins
what are antigens ?
usually glycolipids or glycoproteins