Methoxyflurane

Question 1

Methoxyflurane
Type

Answer 1

Volatile inhalation anaesthetic and analgesic agent

Question 2

Methoxyflurane
Presentation

Answer 2

3ml bottle

Question 3

Methoxyflurane
Action

Answer 3

Central nervous system depressant
Onset 3-5mins Offset 3-5mins

Question 4

Methoxyflurane
Use

Answer 4

For relief of pain of all origins

Question 5

Methoxyflurane
Adverse Effects

Answer 5

1. Altered consciousness
2. Renal dysfunction (rare with once only use)
3. Jaundice (rare with once only use)
4. Uterine atonia

Question 6

Methoxyflurane
Contraindications

Answer 6

1. Depressed level of consciousness
2. Known hypersensitivity
3. malignant hyperthermia
4. concurrent doxycycline use (eg Doryx, Doxsig, Doxylin, Frakas etc)

Question 7

Methoxyflurane
Precautions

Answer 7

1. Renal disease
2. Diabetes
3. caution if patient unable to self administer
4. Use in the post-delivery phase of labour, and with post-partum haemorrhage (may induce uterine atonia)

Question 8

Methoxyflurane
Dose

Answer 8

Adult and Paed
Up to 3ml - self- administered via Penthrox inhaler.
repeat once if required
dose should not exceed 6ml/day or 15ml/week
(if used during labour, discontinue use post-delivery and if PPH is suspected.)