Naloxone

Question 1

Naloxone
Type

Answer 1

Narcotic antagonist

Question 2

Naloxone
Presentation

Answer 2

Varies frequently - check before use

Question 3

Naloxone
Action

Answer 3

Reverses the effects of narcotic analgesics.
IV: onset 1-2mins durations 30-45mins
IM: timing unknown, but thought to have slightly longer onset and duration than when given IV.

Question 4

Naloxone
Uses

Answer 4

1. Coma
2. Drug overdose and poisoning
3. Use in situations where there is significant decrease in level of consciousness; where there is hypoventilation and or loss of protective reflexes; and where overdose of narcotics cannot be positively excluded

Question 5

Naloxone
Adverse Effects

Answer 5

1. May precipitate acute withdrawal syndrome in narcotic addicts
2. Occasional aggressive behaviour following reversal
3. Nausea and vomiting

Question 6

Naloxone
Contraindications

Answer 6

Known hypersensitivity

Question 7

Naloxone
Dose

Answer 7

Adult: 0.8mg IM
Repeat once
or call ICP backup for IV and additional doses
Paed: 0.01mg/kg
Repeat after 2-5mins if no effects
maximum paed dose: 3x calculated doses.
ICP back up for additional doses.