Dog shock organ
GI
Cat shock organ
Lungs
What is the precursor of serotonin (5HT)?
Tryptophan
Total body water distribution
- Water = ___ % of body
- Intracellular = ___ %
- Extracellular = ___ %
- Interstitial = ___ %
- Plasma = ___ %
- Water = 60% of body
- Intracellular = 40%
- Extracellular = 20 %
- Interstitial = 15%
- Plasma = 5%
Osmolality =
Osmolality = 2Na + (Glucose/18) + (BUN/2.8)
- BUN, glue are ineffective osmoles
- Alb is the most potent determinant of oncotic force
What IVF is a hyperosmolar with lower oncotic pressure?
7.5% NaCl
What IVF is an isotonic crystalloid?
D5W
What IVF is a higher oncotic pressure but isotonic?
Dextrans
What IVF is a higher oncotic pressure and hypertonic?
Hetastarch
Which organ is PTHrP NOT normally found in?
Kidney
Examples of organs PTHrP is present normally
Bone, mammary gland, skin
What is cohort study?
A study of a group with a specific characteristic or experience.
What is cross sectional study?
A study of many subjects at the same point in time.
Which administration method is the most susceptible to first pass metabolism? How we can avoid it?
Most susceptible: oral
Can be avoided by transmucosal or rectal administration
What AUC means?
The % of a drug that reaches systemic circulation
If AUC of both curves is equal, bioavailability is 100%.
