Opioids

Question 1

Morphine onset and duration

Answer 1

onset: 15- 30 min
duration: 2 to 3 hours

Question 2

side effects of morphine

Answer 2

histamine release, mania in cats and horses, vomiting

Question 3

Hydromorphone onset and duration

Answer 3

onset: 15 minutes
duration: 4 to 6 hours

Question 4

hydromorphone side effects

Answer 4

vomit from IM admin, panting in dogs, hyperthermia in cats

Question 5

Methadone peak onset and duration

Answer 5

onset: 15 minutes
duration: 4 to 6 hours

Question 6

methadone side effects

Answer 6

no histamine release, no vomiting, panting

good for neuropathic pain

Question 7

Fentanyl onset and duration

Answer 7

onset: 6 to 8 minutes
Duration: 30 to 60 minutes

Question 8

side effects of fentanyl

Answer 8

bradycardia and chest rigidity

Question 9

Buprenorphine onset and duration

Answer 9

onset: 45 to 90 minutes
duration: 6 to 8 hours

Question 10

buprenorphine side effects

Answer 10

plateau effect, not effectively reversed with antagonist

Question 11

butorphanol onset and duration

Answer 11

onset: 10 to 15 minutes
duration: 1 to 2 hours

Question 12

butorphanol side effects

Answer 12

plateau effect, can reverse effects of pure mu agonist

Question 13

naloxone onset and duration

Answer 13

onset: 2 to 5 minutes
duration: 20 to 40 minutes

Question 14

which opiod has the shortest duration of action?

Answer 14

fentanyl

Question 15

which opioids have the longest duration of action?

Answer 15

buprenorphine and tramadol

Question 16

which opiods have a duration of action around 4-6 hours?

Answer 16

methadone and hydromorphone

Question 17

which opioids have a duration of action around 2-3 hours?

Answer 17

morphine and butorphanol