plateles

Question 1

platelets are

Answer 1

small pieces of cytoplasmic fragments
pieces of megakaryocytes
. We have about 150-300 thousand per cubic millimeter of blood. very abundant compared to WBC’s
only last about 10 days
plays a big role in hemostasis

Question 2

hemostasis

Answer 2

stop bleeding
plays big role here

Question 3

step one Vasoconstriction

Answer 3

Narrowing the blood vessels that lead to the wound
Blood vessels have circular muscle fibers so if cut will constrict
This happens when platelets release thromboxane when stimulated only
Blood vessels Simple squamous epidemic tissue releases a chemical called endothelium which is a constrictor

Question 4

step two: formation of platelet plug (bot a clot)

Answer 4

When damage occurs the collagen in the basement membrane is exposed
There is compound called von Willebrand factor that connects platelets to collagen Like it’s a glue.
It will also activate the platelets and attach to each other via fibrin and plug begins to form

Question 5

step three: clot formation

Answer 5

When it forms, we have to convert fibrinogen to fibrin.
Fibrin is a sticky gummy web so when red blood cells go by they get stuck..
To convert fibro is a link to a chain and fibrin is the chain.
To do this process we need an enzyme called prothrombin in the blood

Question 6

step four: thrombosis

Answer 6

This takes place once tissue is healed, the blood clot has to be removed
Require an enzyme called Plasmin which destroys the fibrin

Question 7

clot formation steps

Answer 7

vasoconstriction
formation of platelet plug
clot formation
thrombosis

Question 8

to make a platelet, which stem cell do we need

Answer 8

hemocytoblast with different kind of receptor and hormones to determine what element of the blood is it going to be

Question 9

what hormone are we using to stimulate platelet formation

Answer 9

thrombopoietin

Question 10

the hemocytoblast becomes a

Answer 10

promegakaryocyte
starts to recreate ONLY its nucleus 2-4 times and becomes a megakaryocyte meaning with a large nucleus
- The big nucleus allows a lot of product for the platelets to fill up with prominent stuff that can help with blood

Question 11

last step in the cell will form

Answer 11

little piece of cytoplasm called platelets
This process is called exocytosis

Question 12

the big nucleus allows…

Answer 12

a lot of product for the platelets to fill with prominent stuff that can help with blood clot

Question 13

formation of platelets steps

Answer 13

thrombopoietin
Hemocytoblast
promegakaryocyte
megakaryocyte
platelets