0
Q
Trade Name
A
Diprivan
1
Q
Generic Name
A
propofol
2
Q
Class
A
Sedative hypnotic
3
Q
Mechanism of Action
A
Produces rapid induction of anesthesia by unclear mechanism. Potentiates GABA and blocks sodium channels
4
Q
Indications
A
Induction and maintenance of sedation
5
Q
Contraindications
A
allergies to soy and eggs, increased ICP
6
Q
Adverse Reactions
A
hypotension, local pain on induction, respiratory depression, bradycardia, apnea
7
Q
Dose -> Adult
A
2mg/kg for induction
25-75mcg/kg/min IV drip for maintenance
8
Q
Dose -> Pediatric
A
Not Required
9
Q
Route
A
IV/IO
10
Q
Special Considerations
A
- potentiated by other CNS depressants
- suppresses seizures
- close monitoring of ABCs and VS
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