RNAPII binding

Question 1

What are the five types of proteins required for RNAPII binding?

Answer 1

1) transcription activators 2) architectual regulators 3) chromatin modification/remodeling proteins 4) co-activators and co-repressors 5) basal transcription factors

Question 2

Architectual regulators

Answer 2

facilitate DNA looping (HMG proteins)

Question 3

What is the function of the mediator complex

Answer 3

forms a molecular bridge between activation domains and pol II