Sildenafil

Question 1

What is sildenafil also known as?

Answer 1

Viagra

Question 2

What is the MOA of sildenafil?

Answer 2

It is a phosphodiesterase type V inhibitor

Question 3

What is sildenafil used to treat?

Answer 3

Impotence

Question 4

When is sildenafil contraindicated?

Answer 4

• Patients taking nitrates and related drugs such as nicorandil
• Hypotension
• Recent stroke or myocardial infarction (NICE recommend waiting 6 months)
• Non-arteritic anterior ischaemic optic neuropathy

Question 5

What are some side effects of sildenafil?

Answer 5

• Visual disturbances e.g. blue discolouration, non-arteritic anterior ischaemic neuropathy
• Nasal congestion
• Flushing
• Gastrointestinal side-effects
• Headache