Statins

Question 1

With what drugs should we limit simvastatin use to 20mg?

Answer 1

1. Amlodipine
2. Diltiazem
3. Verapamil
4. Amiodarone

Question 2

With what drugs is simvastatin contraindicated?

Answer 2

• Itraconazole
• Ketoconazole
• Erythromycin
• Clarithromycin
• HIV protease inhibitors
• Ciclosporin

Question 3

In what drugs should simvastatin mostly be reduced to 10mg?

Answer 3

Most fibrates.

Simvastatin should not be used at all with Gemfibrozil.

Simvastatin dose can be higher with fenofibrate.