Causative agents responsible
are organisms commonly found
in soil or on decaying vegetation
subcutaneous mycoses
subcutaneous mycoses Belong to a variety of genera in the
form class ______
Hyphomycetes
in SubCu Mycoses Although some are moniliaceous (hyaline or light-colored), many are phaeoid, producing darkly pigmented colonies and containing
melanin in their cell walls. (t/f)
true
Also known as rose
handler’s disease, is a fungal infection that affects skin, lungs, bone and joint, and can be widespread. it presents with firm painless nodules
that later ulcerate.
sporotrichosis
a longterm fungal infection of the skin and subcutaneous tissue (a chronic subcutaneous mycosis).
chromoblastomycosis
alsO known as Madura foot,
isa persistent fungal infection of the skin and the tissues just under the skin, affecting most commonly the feet, although it can occur in hands and other body parts. It starts as a painless wet nodule, which may be
present for years before ulceration, swelling, grainy discharge and weeping from sinuses and fistulae, followed by bone deformity
eumycetoma
chromoblastomycosis aka:
verrucous dermatitis; chromomycosis
Mostly asymptomatic in the absence of secondary complications
(e.g. bacterial infections, carcinomatous degeneration, and elephantiasis)
chromoblastomycosis
in chromoblastomycosis
________ are usually confined to the extremities, often the _____and
_______, and are a result of trauma to these areas
lesion
feet
lower legs
in chromoblastomycosis
______, ______sclerotic bodies (_____ ______ bodies), which are non-budding structures
occurring singly or in clusters, are seen in tissues
These sclerotic bodies reproduce by dividing in various planes, resulting in multicellular forms.
brown
round
copper penny
diagnositc for chromoblastomycosis
presence of sclerotic bodies
chromoblastomycosis
Presents wart-like lesions on exposed areas of the skin (can excess ____cm in diameter)
Patches of skin may appear flattened (plaque-like) and show _____ or _____, but they are not itchy or painful
Large lesions cause severe limb
swelling and discomfort, limiting
movement
10
central scarring or atrophy
chromoblastomycosis
culture:
Growth is moderate to slow
colonies appear velvety to wooly
gray-brown to olivaceous black
Species are not differentiated by colony morphologies
because they all produce similar characteristics
chromoblastomycosis
An infection of the subcutaneous tissues that arises at the
site of inoculation
Characterized by swelling, with characteristic exudate
draining to the skin surface through sinus tracts
Mycetomas may be caused by fungi or bacteria
eumycotic mycetoma
mycetoma caused by:
bacteria -
fungi 0
actinomycotic mycetoma
eumycotic mycetoma
The anamorphic form of P. boydii is
the septate filamentous fungus -
________
Scedosporium boydii
It produces oval conidia singly at the tips of conidiogenous cells known as annellides
Pseudallescheria boydii
Pseudallescheria boydii
The telemorph is noted
by the formation of
______ containing
ascospores
cleistothecia
Produces mucoid clusters of
single or two-celled, slightly
curved conidio borne from
phialides at the tips of the long,
unbranched, multiseptate
conidiophores
Fusarium (Acremonium) falciforme
Grows very slowly but is initially white, and becomes yellow, olivaceous, or brown, with a characteristic diffusible
brown pigment with age
Grows best at 37°C, with slower
growth at 40°C
Madurella spp.
Only sterile hyphae are observed
Isolate grows slowly, produce
olive brown to black colonies,
and may produce reddish brown
pigment.
Optimal growth is 30°C
Madurella grisea
conidia are borne from
annellides, with conidia
aggregating in masses at the
tips of the conidiophores
Exophiala spp.
Forms conidia at the tip of
phialides
Produces olivaceous to black
colonies that are initially yeast-like
but become vevelty at maturity
Exophiala dermatitis
