Transplant

Question 1

Top 3 malignancies post transplant

Answer 1

1. Squamous cell cancer of skin
2. PTLD
3. Basal cell cancer of skin

Question 2

Immediate allergic reactions mediated by which cytokine

Answer 2

IL-4 (causes IgE production and mast cell activation)

Question 3

Hyeracute rejection histology and immune reaction

Answer 3

endothelial damage, antibodies and complement

Question 4

Acute rejection histology and immune reaction

Answer 4

lymphocyte infiltration and necrosis; T cells

Question 5

Chronic rejection histology and immune reaction

Answer 5

Fibrosis; T cell and B cells

Question 6

Cytokine responsible for allergic reaction due to activation of eosinophils

Answer 6

IL-5

Question 7

Monoclonal antibody to CD20

Answer 7

Rituximab

Question 8

1 and 5 year graft survival for living donor kidney transplsnt

Answer 8

97% and 85%