TXA

Question 1

What is the MoA of TXA?

Answer 1

Antifibrinolytic - Binds to plasminogen, decreasing conversion to plasmin, and theyeby prevents fibrin degradation

Question 2

Presentation of TXA

Answer 2

1g/10mL

Question 3

What is the contraindication of TXA

Answer 3

• Injury occurred > 2hours prior to administration

Question 4

What is the precaution of TXA

Answer 4

• Rapid administration increases the risk of adverse effects

Question 5

What are the adverse effects of TXA

Answer 5

CNS: Seizures
CVS: Hypotension, Dizziness
GIT: Nausea, vomiting, diarrhoea

Question 6

How is TXA prepared for infusion

Answer 6

• Added to 100mL dextrose OR Normal Saline

Question 7

How many drops is TXA infused over?

Answer 7

10minutes ROUGHLY 3drops per second

Question 8

How is IM TXA given

Answer 8

Two 5mL injections into the lateral thigh