u4 - intro Flashcards

(38 cards)

1
Q

homeostatsis

A

method to keep a stable environment, esp internally

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2
Q

main components of homeostasis

A
  1. receptor
  2. control centre
  3. effector
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3
Q

hypothalamus and pituitary

A

hypothalamus detects changes and signals to pituitary for response. pituitary releases and prod hormones

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4
Q

posterior pituitary

A

stores adn releases hormones

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5
Q

anterior pituitary

A

makes and releases hormones

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6
Q

hormones

A

chemicals released by cells that are located in glands that affect other cells
- chemical regulation ,travel to target cells

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7
Q

steriod hormones

A

made from cholesterol (fat soluble) in sex organs and adrenal glands (cortisol, estrogen , testosterone)

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8
Q

role of steroid horomes

A

regulates metabolism, inflammation, immune function

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9
Q

how steroid hormones travel thru body

A

in blood, bound to plasma protein carriers and diffuse into cell

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10
Q

how steroid hormones changes a cell

A
  1. hormone enters target cell
  2. binds w receptor protein
  3. hormone receptor complex enters nucleus
  4. complex binds w dna
  5. mrna copy made of gene
  6. mrna is read by ribosomes and protein made
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11
Q

protein hormones

A

made from amino acids (water soluble), incl insulin, growth hormones, thyroxine

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12
Q

how protein hormones change a cell

A
  1. hormones travel in blood and attach to receptor protein on cell membrane
  2. receptor protein complex activates secondary enzymes on cell membrane
  3. activated enzymes = from cAMP (cycle AMP from ATP)
  4. cAMP acts as manager, triggering cellular processes to carry out normal function
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13
Q

hypersecretion

A

more hormones are released than normal

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14
Q

hyposecretion

A

less hormones are released than normal (little to no change)

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15
Q

hormones that control bblood sugar lvls

A

insulin (beta cells), glucagon (alpha cells)

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16
Q

where are insulin and glucagon made

A

pancreas (islets of Langerhans)

17
Q

whats released when blood sugar is high

A

insulin
- inc permeability of cells to glucose
- glucose conv to glycogen, stored in liver
- blood sugar lvl drops

18
Q

whats released when blood sugar is low

A

glucagon
- conv glycogen to glucose
- blood sugar lvl inc

19
Q

role of adrenal medulla

A

fight or flight, short term stress response

20
Q

role of adrenal cortex

A

long term stress response

21
Q

acute (shortterm) stress response

A
  1. msgs are sent from hypothalamus –> spinal cord nerves –> adrenal medulla
  2. adrenal medulla releases adrenaline/noradrenaline
  3. blood vessels and iris dialate, inc blood sugar lvl, heart/breathing/metabolic rate
22
Q

chronic (long term) stress reponse

A
  1. hypothalamus releases acth –> adrenal cortex
  2. adrenal cortex secretes CORTISol (inc aa in blood conv to glucose for cellresp and protein synth) & aldosterone (inc sodium retention in kidneys, inc blood volume/pressure)
  3. inc bp –> inc blood clotting (risk of heart attack/stroke) –> inc cellresp and heeartrate, damage heart muscle
23
Q

low calcuim what happens

A

parathyroid gland prod pth –> kidneys and gut retain calcium //bones release calcium

24
Q

high calcium what happens

A

thyroid gland releases calcitonin, deposits calcium in bone

25
what does thyroid gland also release and what does it do
t3, t4, used for gorwth/differentiaton of tissues, regulating metabolism
26
what happens when metabolic rate dec
hypothalamus secretes thyroid releasing hormone (trh), pituitary releases thyroid stimulating hormone (tsh) - tsh activates thyroid gland to release t3,t4
27
negative feedback loop built into response to low metabolism
high lvls of thyroxine cause pathways to be turned off (for rleeasing t3, t4)
28
hypothyroidism
caused by lack of iodine, cancer, genetic disorder, results in an enlarged thyroid, prod goiter
29
hyperthyroidism
caused by autoimmune disease (graves disease), inflammation, overactive nodules, results in overprod of tsh, t3,t4 (accerlerated metabolsim)
30
shared symptoms of hypo/hyperthyroidsm
fatigue, insomnia, hair loss
31
symptoms of hypothyroidism
slow heartrate, irregular/heavy period, dec sweating
32
symptoms of hyperthyroidism
fast hr, short/light periods, inc sweating
33
hypothyroid treatments
synthetic t4
34
hyperthyroid treatements§
antithyroid meds, radioactive iodine, surgery
35
growth hormone
somatotropin, inc cell size in muscle and connective tissue
36
low amt of growth hormone released in childhood
dwarfism
37
high amt of growth hormone released in childhood
gigantism
38
high amt of growth hormone released during adulthood
acromegaly