Week 9 Flashcards

(56 cards)

1
Q

the spleen is what type and located where?

A

Intraperitoneal in the LUQ

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2
Q

What system is the spleen a part of?

composed primarily of?

A

Reticuloendothelial system

Composed primarily of lymph tissue

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3
Q

the spleen is responsible for…

active in…

A

Responsible for the phagocytosis of damaged/old cells, foreign material and pathogens

Active in hematopoiesis during the first part of fetal life

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4
Q

spleen plays an important role in…

NOT essential to

A
  • Plays an important role in the body’s defense
    against disease
  • NOT essential to life
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5
Q

specific location of spleen?

posterolateral to the…

posterior to…

A

Left hypochondrium

Posterolateral to the body and fundus of the stomach and pancreatic tail

  • Posterior to the left colic gutter
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6
Q

LK is posteroinferior to what part of the spleen

A
  • LK is posteroinferior to the medial section
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7
Q

The spleen is anterior to…

A

Diaphragm, left lung, ribs, left pleura

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8
Q

the splenic hilum is medial where…

the only portion that is not…

because of its locations the ribs offer…

A
  • Medial where the vessels enter and exit, the only portion that is not covered by peritoneum
  • Because if it’s location the ribs offer much needed protection of the spleen.
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9
Q

spleen is between the left …. and the …

A

Between the left hemidiaphragm and the
stomach

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10
Q

the spleen is lateral to…

A

Stomach and lesser sac

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11
Q

LK is _______ to the spleen

A

LK is inferomedial

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12
Q

size of the spleen?

in its longest dimension should not exceed…

contour…

________ superior surface and _______ inferior surface

A

In its longest dimension should not exceed
13cm

  • Smooth in contour
  • Convex superior surface and concave inferior
    surface
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13
Q

spleen type (in relation to blood flow)

______ superiorly and ______ inferiorly

covered in _______ with the exception of the…

A

Highly vascular lymphoid tissue

Ovoid structure, convex superiorly and
concave inferiorly

Covered in peritoneum with the exception of
the hilum

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14
Q

spleen is composed of…

A

white and red pulp

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15
Q

White pulp

what is it?

consists of?

what surrounds the arteries and are scattered throughout the spleen

A
  • Lymphatic tissue that surrounds and follows the
    smaller splenic arteries
  • Consists of the Malpighian corpuscles
    –> Small nodular masses of lymphoid tissue attached to smaller arterial branches
  • Lymphoid tissue follicles surround arteries and are scattered throughout the spleen
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16
Q

Red pulp

contains a large number of…

fills the remaining space of the _______, surrounds…

consists of …

_____ are permeable, RBCs can enter the…

A
  • More vascular, contain large numbers of RBCs
  • Fills the remaining spaces of the lobules, surrounds venous sinuses
  • Consists of splenic sinuses and splenic cords
  • Capillaries are permeable → RBCs can enter the
    venous sinuses
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17
Q

SPL A originates from _______
–> courses…
–> pancreatic branches and gastric branches arise from …

A

celiac trunk
* Courses laterally towards the spleen
* Pancreatic branches and gastric branches arise
from SPL A

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18
Q

The SPL A at the hilum branches into

These further branch into…

A

2-4 lobar arteries

lobular arteries then smaller splenic arteries that terminate in capillaries

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19
Q

The capillaries help with the

A

filtering function of the spleen

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20
Q

The capillaries anastomose with…

Theses _______ converge to form the SPL V

SPL V courses medially to the confluence with
the IMV/SMV to form the __________

A

tiny venous sinuses that form splenic venules

venules

SPL V courses medially to the confluence with
the IMV/SMV to form the portal vein

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21
Q

Lymph vessels emerge from the _________,
pass through other lymph nodes along the
course of the splenic artery, and drain into the
_________.

A

Lymph vessels emerge from the splenic hilum,
pass through other lymph nodes along the
course of the splenic artery, and drain into the
celiac nodes.

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22
Q

Nerves to the spleen accompany the _______ and are derived from the _______

A

Nerves to the spleen accompany the splenic
artery and are derived from the celiac plexus

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23
Q

The spleen helps remove _______, ______, _____ and
_______

A

Help remove old cells, debris, pathogens and
foreign substances

24
Q

the spleen produces…

A
  • Lymphocytes, phagocytes, plasma cells and
    antibodies
  • RBCs and WBCs
25
the spleen stores
iron and metabolites
26
the spleen acts as a... and regulates...
* Acts as a reservoir for blood * Regulates platelet and leukocyte life span
27
4 major functions of the spleen
* Defense * Hematopoiesis * RBC and platelet destruction * Blood reservoir
28
How does spleen aid in defence
* Aids in destruction and removal of microorganisms by phagocytosis * White pulp produces lymphocytes and monocytes that are active in ingestion and digestion of harmful pathogens * Plasma cells destroy invading microorganisms * Memory cells remember the pathogen and if the body is attacked again they produce the antibodies rapidly to destroy it --> Immune response
29
How does spleen perform Hematopoiesis
* Produces erythrocytes (RBC) and WBCs in the developing fetus * Only performed in adults suffering from severe hemolytic anemia
30
How does spleen perform RBC Removal
* Abnormal/old RBCs and platelets are removed * The blood travels through the red pulp and into the sinuses --> These are filters that help with phagocytosis of old RBCs --> Pitting: the removal of nuclei from old RBCs without damaging the cell --> Culling: removal of Abn RBCs * The hemoglobin in these are broken down, the iron is either used immediately for more RBCs or transported to the liver and bone marrow for storage
31
What is pitting?
the removal of nuclei from old RBCs without damaging the cell
32
what is culling?
removal of Abn RBCs
33
The hemoglobin in blood is broken down by spleen and what happens to the iron?
the iron is either used immediately for more RBCs or transported to the liver and bone marrow for storage
34
how does the spleen perform the function of storage?
* The high smooth muscles content gives the ability to store RBCs – blood reservoir * Held in the red pulp * Can be released instantaneously if needed\ * If the number of cells is excessive --> splenomegaly
35
Hematocrit
* Indicates the percentage of RBCs per volume of blood. * Abnormally low readings can indicate hemorrhage or internal bleeding within the body.
36
Bacteremia
* Indicates the presence of bacteria within the body. * The term sepsis indicates bacteria in the bloodstream. * Typical symptoms of fever and chills, along with other medical conditions, may
37
Leukocytosis
* The increase in the number of WBCs present in the bloodstream is usually a typical finding in infection. * This finding may also occur after surgery, in malignancies, or in the presence of leukemia
38
Leukopenia
* Abnormal decrease in white blood corpuscles * May be secondary to certain medications or bone marrow disorder
39
Thrombocytopenia
* Abnormal decrease in platelets * May be the result of internal hemorrhage
40
Spleen is typically best seen in...
Typically best seen in the intercostal window
41
In sagittal view the spleen and ____ can be visualized
LK
42
Normal variants (NUMBER)
- Accessory - Asplenia - Polysplenia
43
Normal variants (Location)
- Wandering - Ectopic
44
Accessory Spleen
Splenule Typically found near the hilum or inferior border of spleen
45
Asplenia
is the complete absence of the spleen
46
Polysplenia
Multiple small accessory spleens
47
Wandering spleen
is a spleen that has migrated from its normal location in the left upper quadrant.
48
Ectopic
The spleen is located in the abdominal cavity outside of where it should be
49
Ellipsoid formula (Measuring to Calculate Splenic Volume)
(length × width × depth × 0.523)
50
Measuring the spleen for volume
measure 2x in long, x1 in trans
51
Lymphatics contains...
- Lymph - lymphatic vessels - lacteals - lymph nodes and spleen - bone marrow - thymus gland
52
lymphatics typically has how many lymph nodes? where does it cluster?
~ 500 to 600 Clusters in the axillae, groin, neck, chest, and abdomen
53
Function of lymphatics?
* Collect and transport excess fluids, lymph, from interstitial spaces back into the venous system * Absorb fats from small intestine and transport them to the liver * Utilize lymphoid tissue and organs to produce cells that fight (immune system) and dispose of foreign material
54
Size of normal nodes?
Less than 1cm * Not normally imaged with ultrasound * Typically seen when abnormal
55
Common sites for lymph nodes
* Paraaortic and paracaval areas near the great vessels * Peripancreatic area * Renal hilar area * Mesenteric region
56
lymph node consists of the ______ and ______
Consists of the cortex and hilum